Genome-wide association study of serum magnesium in type 2 diabetes
LJ Oost, RC Slieker, MT Blom, LM 't Hart… - Genes & nutrition, 2024 - Springer
People with type 2 diabetes have a tenfold higher prevalence of hypomagnesemia, which is
suggested to be caused by low dietary magnesium intake, medication use, and genetics …
suggested to be caused by low dietary magnesium intake, medication use, and genetics …
Magnesium Intake, Genetic Variants, and Diabetes Risk
Type 2 diabetes mellitus (DM) is a major global public health burden, affecting more than
170 million individuals worldwide [1]. Overall, it is estimated that the prevalence of diabetes …
170 million individuals worldwide [1]. Overall, it is estimated that the prevalence of diabetes …
Serum magnesium and the risk of prediabetes: a population-based cohort study
Aims/hypothesis Previous studies have found an association between serum magnesium
and incident diabetes; however, this association may be due to reverse causation, whereby …
and incident diabetes; however, this association may be due to reverse causation, whereby …
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels
TE Meyer, GC Verwoert, SJ Hwang, NL Glazer… - PLoS …, 2010 - journals.plos.org
Magnesium, potassium, and sodium, cations commonly measured in serum, are involved in
many physiological processes including energy metabolism, nerve and muscle function …
many physiological processes including energy metabolism, nerve and muscle function …
Dietary magnesium and genetic interactions in diabetes and related risk factors: a brief overview of current knowledge
A Hruby, NM McKeown, Y Song, L Djoussé - Nutrients, 2013 - mdpi.com
Nutritional genomics has exploded in the last decade, yielding insights—both nutrigenomic
and nutrigenetic—into the physiology of dietary interactions and our genes. Among these …
and nutrigenetic—into the physiology of dietary interactions and our genes. Among these …
[HTML][HTML] Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 …
A Hruby, JS Ngwa, F Renström, MK Wojczynski… - The Journal of …, 2013 - Elsevier
Favorable associations between magnesium intake and glycemic traits, such as fasting
glucose and insulin, are observed in observational and clinical studies, but whether genetic …
glucose and insulin, are observed in observational and clinical studies, but whether genetic …
[HTML][HTML] Genetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American women
KHK Chan, SA Chacko, Y Song, M Cho, CB Eaton… - The Journal of …, 2015 - Elsevier
Background: Prospective studies consistently link low magnesium intake to higher type 2
diabetes (T2D) risk. Objective: We examined the association of common genetic variants …
diabetes (T2D) risk. Objective: We examined the association of common genetic variants …
Meta‐analysis of interaction between dietary magnesium intake and genetic risk variants on diabetes phenotypes in the CHARGE Consortium
A Hruby, JS Ngwa, JB Meigs, JA Nettleton… - 2012 - Wiley Online Library
Little is known about whether genetic variation modifies the effect of magnesium (Mg) intake
on two important diabetes risk factors: fasting glucose (FG) and insulin (FI). We examined …
on two important diabetes risk factors: fasting glucose (FG) and insulin (FI). We examined …
Genome-wide association study reveals two loci for serum magnesium concentrations in European-American children
Magnesium ions are essential to the basic metabolic processes in the human body.
Previous genetic studies indicate that serum magnesium levels are highly heritable and a …
Previous genetic studies indicate that serum magnesium levels are highly heritable and a …
Association of serum magnesium with insulin resistance and type 2 diabetes among adults in China
W Li, Y Jiao, L Wang, S Wang, L Hao, Z Wang, H Wang… - Nutrients, 2022 - mdpi.com
Magnesium is an essential mineral for the human body and a cofactor or activator for more
than 300 enzymatic reactions, including blood glucose control and insulin release. Diabetes …
than 300 enzymatic reactions, including blood glucose control and insulin release. Diabetes …