Whole-body autoradiography (WBA) is a technique that has been available for many years
for studying the biological fate of chemicals. This technique, which is most frequently …

Whole-body autoradiography (WBA) is a technique used to obtain comprehensive data on
the tissue distribution of a chemical. It allows specific sites of localization to be observed …

This chapter attempts to describe the development and use of autoradiography in the
laboratory. Imaging plates allow similar intensity autoradiograms to be acquired in a fraction …

The development of the research on xenobiotics has made it necessary to improve our
knowledge of the action of such compounds on living systems. While the pharmacological or …

Traditional bioanalytical measurements determine concentrations of drug and metabolites in
plasma; however, most drugs exert their effects in defined target tissues. As there is no clear …

Distribution studies with new radiolabeled test compounds in animals form an important part
in the preclinical drug development programs of many companies. The data obtained from …

Autoradiography (ARG) is a powerful, high resolution, quantitative molecular imaging
technique used to study the tissue distribution of radiolabeled xenobiotics in biological …

A practical laboratory manual gives details of the use of whole-body autoradiography in
studying the distribution, toxicity and therapeutic effects of substances in the tissues and …

Radiolabeled drugs have been widely used in drug discovery and development studies
since radioactivity can easily be detected and quantified using liquid scintillation techniques …

Autoradiography is widely used in toxicological and pharmacological studies to determine
biotransformation, distribution and excretion of compounds. The first part of this review …