Manufacturing techniques and surface engineering of polymer based nanoparticles for targeted drug delivery to cancer

Y Wang, P Li, T Truong-Dinh Tran, J Zhang, L Kong - Nanomaterials, 2016 - mdpi.com
The evolution of polymer based nanoparticles as a drug delivery carrier via pharmaceutical
nano/microencapsulation has greatly promoted the development of nano-and micro …

Biodegradable polymeric nanoparticles based drug delivery systems

A Kumari, SK Yadav, SC Yadav - Colloids and surfaces B: biointerfaces, 2010 - Elsevier
Biodegradable nanoparticles have been used frequently as drug delivery vehicles due to its
grand bioavailability, better encapsulation, control release and less toxic properties. Various …

Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

Recent advances in the surface functionalization of PLGA-based nanomedicines

MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …

Nanoparticle-based drug delivery systems for cancer therapy

Y Dang, J Guan - Smart Materials in Medicine, 2020 - Elsevier
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …

Tuning the size of poly (lactic‐co‐glycolic acid)(PLGA) nanoparticles fabricated by nanoprecipitation

W Huang, C Zhang - Biotechnology journal, 2018 - Wiley Online Library
Polymeric nanoparticles (PNPs) are promising drug carriers in cancer treatment. Size of the
particles has a significant impact on drug loading, in vivo distribution, extravasation …

PLGA nanoparticles and their versatile role in anticancer drug delivery

I Khan, A Gothwal, AK Sharma… - Critical Reviews™ in …, 2016 - dl.begellhouse.com
Nanotechnological advancement has become a key standard for the diagnosis and
treatment of several complex disorders such as cancer by utilizing the enhanced …

Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid

CG Keum, YW Noh, JS Baek, JH Lim… - International journal …, 2011 - Taylor & Francis
Background Nanoparticles fabricated from the biodegradable and biocompatible polymer,
polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug …

Concepts and practices used to develop functional PLGA-based nanoparticulate systems

H Sah, LA Thoma, HR Desu, E Sah… - International journal of …, 2013 - Taylor & Francis
The functionality of bare polylactide-co-glycolide (PLGA) nanoparticles is limited to drug
depot or drug solubilization in their hard cores. They have inherent weaknesses as a drug …

Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile

P Rafiei, A Haddadi - International journal of nanomedicine, 2017 - Taylor & Francis
Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer
types. There are important matters of concern regarding the drug's pharmacokinetics related …