Manufacturing techniques and surface engineering of polymer based nanoparticles for targeted drug delivery to cancer
The evolution of polymer based nanoparticles as a drug delivery carrier via pharmaceutical
nano/microencapsulation has greatly promoted the development of nano-and micro …
nano/microencapsulation has greatly promoted the development of nano-and micro …
Biodegradable polymeric nanoparticles based drug delivery systems
Biodegradable nanoparticles have been used frequently as drug delivery vehicles due to its
grand bioavailability, better encapsulation, control release and less toxic properties. Various …
grand bioavailability, better encapsulation, control release and less toxic properties. Various …
Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics
D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …
Recent advances in the surface functionalization of PLGA-based nanomedicines
MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
Nanoparticle-based drug delivery systems for cancer therapy
Y Dang, J Guan - Smart Materials in Medicine, 2020 - Elsevier
Nanoparticle-based drug delivery system (DDS) is considered promising for cancer
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …
treatment. Compared with traditional DDS, the nanoparticle-based DDS shows improved …
PLGA nanoparticles and their versatile role in anticancer drug delivery
Nanotechnological advancement has become a key standard for the diagnosis and
treatment of several complex disorders such as cancer by utilizing the enhanced …
treatment of several complex disorders such as cancer by utilizing the enhanced …
Tuning the size of poly (lactic‐co‐glycolic acid)(PLGA) nanoparticles fabricated by nanoprecipitation
Polymeric nanoparticles (PNPs) are promising drug carriers in cancer treatment. Size of the
particles has a significant impact on drug loading, in vivo distribution, extravasation …
particles has a significant impact on drug loading, in vivo distribution, extravasation …
Concepts and practices used to develop functional PLGA-based nanoparticulate systems
H Sah, LA Thoma, HR Desu, E Sah… - International journal of …, 2013 - Taylor & Francis
The functionality of bare polylactide-co-glycolide (PLGA) nanoparticles is limited to drug
depot or drug solubilization in their hard cores. They have inherent weaknesses as a drug …
depot or drug solubilization in their hard cores. They have inherent weaknesses as a drug …
Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid
CG Keum, YW Noh, JS Baek, JH Lim… - International journal …, 2011 - Taylor & Francis
Background Nanoparticles fabricated from the biodegradable and biocompatible polymer,
polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug …
polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug …
Docetaxel-loaded PLGA and PLGA-PEG nanoparticles for intravenous application: pharmacokinetics and biodistribution profile
Docetaxel is a highly potent anticancer agent being used in a wide spectrum of cancer
types. There are important matters of concern regarding the drug's pharmacokinetics related …
types. There are important matters of concern regarding the drug's pharmacokinetics related …