Aging of the vasculature plays a central role in morbidity and mortality of older people. To
develop novel treatments for amelioration of unsuccessful vascular aging and prevention of …

Age-related pathological alterations of the vasculature have a critical role in morbidity and
mortality of older adults. In epidemiological studies, age is the single most important …

This review focuses on molecular, cellular, and functional changes that occur in the
vasculature during aging; explores the links between mitochondrial oxidative stress …

Ageing leads to a progressive deterioration of structure and function of all organs over the
time. During this process endothelial cells undergo senescence and manifest significant …

Vascular aging is a key process determining health status of aged population. Aging is an
independent cardiovascular risk factor associated to an impairment of endothelial function …

Ageing constitutes the biggest risk factor for poor health and adversely affects the integrity
and function of all the cells, tissues, and organs in the human body. Vascular ageing …

Aging is the main risk factor contributing to vascular dysfunction and the progression of
vascular diseases. In this review, we discuss the causes and mechanisms of vascular aging …

Aging causes a progressive decline in the structure and function of organs. With advancing
age, an accumulation of senescent endothelial cells (ECs) contributes to the risk of …

Advancing age promotes cardiovascular disease (CVD), the leading cause of death in the
United States and many developed nations. Two major age-related arterial phenotypes …

A decline in the function of the microvasculature occurs with ageing. An impairment of
endothelial properties represents a main aspect of age-related microvascular alterations …