Nanoparticles in ocular applications and their potential toxicity

C Yang, J Yang, A Lu, J Gong, Y Yang, X Lin… - Frontiers in molecular …, 2022 - frontiersin.org
Nanotechnology has been developed rapidly in recent decades and widely applied in
ocular disease therapy. Nano-drug delivery systems overcome the bottlenecks of current …

Toxicity of nanomaterials to the eye

TW Prow - Wiley Interdisciplinary Reviews: Nanomedicine and …, 2010 - Wiley Online Library
What do nanoparticles offer drug delivery to the eye that traditional formulations do not? The
underlying concept of nanomedicine is that the nanomaterials have properties that their …

Safety and toxicity of nanomaterials for ocular drug delivery applications

NK Mehra, D Cai, L Kuo, T Hein, S Palakurthi - Nanotoxicology, 2016 - Taylor & Francis
Multifunctional nanomaterials are rapidly emerging for ophthalmic delivery of therapeutics to
facilitate safe and effective targeting with improved patient compliance. Because of their …

Emerging nano-formulations and nanomedicines applications for ocular drug delivery

D Khiev, ZA Mohamed, R Vichare, R Paulson, S Bhatia… - Nanomaterials, 2021 - mdpi.com
Ocular diseases can deteriorate vision to the point of blindness and thus can have a major
impact on the daily life of an individual. Conventional therapies are unable to provide …

Nano-ophthalmology: Applications and considerations

MA Kamaleddin - Nanomedicine: Nanotechnology, Biology and Medicine, 2017 - Elsevier
The advent of nanotechnology promises to drastically accelerate progress toward
nanomedicine. Nanoscale particles in the size range of cellular and molecular structures …

[HTML][HTML] Impacts of nanomedicines in ocular pharmacotherapy

A Nakhlband, J Barar - BioImpacts: BI, 2011 - ncbi.nlm.nih.gov
Methods Recent published articles related to applications of ocular nanomedicines were
reviewed and highlighted in this review article. Results It seems the emergence of …

Safety assessment of nanomaterials to eyes: an important but neglected issue

S Zhu, L Gong, Y Li, H Xu, Z Gu, Y Zhao - Advanced Science, 2019 - Wiley Online Library
The production and application of nanomaterials have grown tremendously during last few
decades. The widespread exposure of nanoparticles to the public is provoking great …

Ocular disposition, pharmacokinetics, efficacy and safety of nanoparticle-formulated ophthalmic drugs

HZ Bu, HJ Gukasyan, L Goulet, XJ Lou… - Current drug …, 2007 - ingentaconnect.com
Ophthalmic drugs are delivered to ocular tissues predominantly via relatively simple
formulations, such as topically dosed water-soluble drug solutions and water-insoluble drug …

Overview of recent advances in nano-based ocular drug delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

The role of nanotechnology in control of human diseases: perspectives in ocular surface diseases

M Rai, AP Ingle, S Gaikwad, FH Padovani… - Critical reviews in …, 2016 - Taylor & Francis
Nanotechnology is the creation and use of materials and devices on the same scale as
molecules and intracellular structures, typically less than 100 nm in size. It is an emerging …