Selective cerebellar atrophy associates with depression and fatigue in the early phases of relapse-onset multiple sclerosis

A Lazzarotto, M Margoni, S Franciotta, S Zywicki… - The Cerebellum, 2020 - Springer
Cerebellar dysfunctions have been associated to depressive disorders and cognitive
impairment in neurodegenerative diseases. The objective is to analyze the associations …

[HTML][HTML] Regional cerebellar volume loss predicts future disability in multiple sclerosis patients

K Parmar, VS Fonov, Y Naegelin, M Amann, J Wuerfel… - The Cerebellum, 2022 - Springer
Cerebellar symptoms in multiple sclerosis (MS) are well described; however, the exact
contribution of cerebellar damage to MS disability has not been fully explored. Longer-term …

Cognitive impairment and the regional distribution of cerebellar lesions in multiple sclerosis

SM Tobyne, WB Ochoa, JD Bireley… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Cerebellar lesions are often reported in relapsing-remitting multiple sclerosis
(RRMS) and have been associated with impaired motor function and cognitive status …

The role of cerebellar damage in explaining disability and cognition in multiple sclerosis phenotypes: a multiparametric MRI study

R Bonacchi, A Meani, E Pagani, O Marchesi… - Journal of …, 2022 - Springer
Background Cerebellar involvement is not comprehensively studied from an MRI point of
view in multiple sclerosis (MS). We aimed to quantify cerebellar damage and identify …

[HTML][HTML] Cerebellar abnormalities contribute to disability including cognitive impairment in multiple sclerosis

K Weier, IK Penner, S Magon, M Amann, Y Naegelin… - PloS one, 2014 - journals.plos.org
The cerebellum is known to be involved not only in motor but also cognitive and affective
processes. Structural changes in the cerebellum in relation to cognitive dysfunction are an …

Cognitive deficits in multiple sclerosis patients with cerebellar symptoms

P Valentino, A Cerasa, C Chiriaco… - Multiple Sclerosis …, 2009 - journals.sagepub.com
Background Cerebellar dysfunction is common in patients with multiple sclerosis (MS).
However, neuropsychological studies of this clinical feature are lacking. Objective We …

Evidence for early, non-lesional cerebellar damage in patients with multiple sclerosis: DTI measures correlate with disability, atrophy, and disease duration

M Deppe, K Tabelow, J Krämer… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: Common symptoms of multiple sclerosis (MS) such as gait ataxia, poor
coordination of the hands, and intention tremor are usually the result of dysfunctionality in …

[HTML][HTML] Microstructural analyses of the posterior cerebellar lobules in relapsing-onset multiple sclerosis and their implication in cognitive impairment

A Moroso, A Ruet, D Lamargue-Hamel, F Munsch… - PLoS …, 2017 - journals.plos.org
Background The posterior cerebellar lobules seem to be the anatomical substrate of
cognitive cerebellar processes, but their microstructural alterations in multiple sclerosis (MS) …

MR imaging and cognitive correlates of relapsing–remitting multiple sclerosis patients with cerebellar symptoms

A Cerasa, P Valentino, C Chiriaco, D Pirritano… - Journal of …, 2013 - Springer
Multiple sclerosis (MS) is a demyelinating disease affecting the central nervous system,
frequently associated with cognitive impairments. Damages of the cerebellum are very …

Cerebellar-parietal dysfunctions in multiple sclerosis patients with cerebellar signs

A Cerasa, L Passamonti, P Valentino, R Nisticò… - Experimental …, 2012 - Elsevier
Consistent findings have shown that the cerebellum is critically implicated in a broad range
of cognitive processes including executive functions. Of note, cerebellar symptoms and a …