Hyperuricemia is the result of increased production and/or underexcretion of uric acid.
Hyperuricemia has been epidemiologically associated with multiple comorbidities, including …

This review aims to put forth an overview of natural products reducing uric acid level with
hepatorenal dual effects. The prevalence of hyperuricemia increased rapidly in recent years …

Disorders of uric acid metabolism may be associated with pathological processes in many
diseases, including diabetes mellitus, cardiovascular disease, and kidney disease. These …

Introduction Hyperuricemia is a common metabolic disease, which is a risk factor for gouty
arthritis and ureteral stones and may also lead to cardiovascular and chronic kidney disease …

The prevalence of gout has increased markedly in the United States in the past two
decades, and new treatments for hyperuricemia are being developed. Recent molecular …

Hyperuricemia is a common disease caused by a high level of uric acid. Urate transporter 1
(URAT1) is an important protein and mediates approximately 90% of uric acid reabsorption …

Chronic kidney disease (CKD) has become a global public health issue and uric acid (UA)
remains a major risk factor of CKD. As the main organ for the elimination of UA, kidney …

Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Uric acid (UA) forms monosodium urate (MSU) crystals to exert proinflammatory actions,
thus causing gout arthritis, urolithiasis, kidney disease, and cardiovascular disease. UA is …

Gout is a chronic inflammatory disease caused by precipitation of urate crystals in the joints,
kidneys, and urinary tract. Independent of urate deposition disorders, recent studies have …