The human HSP70 family is a type of heat shock protein (HSP), consisting of 13 members
encoded by the HSPA genes. HSPs play important roles in regulating cellular responses …

Background The HSP70 family of heat shock protein plays a critical role in protein synthesis
and transport to maintain protein homeostasis. Several studies have indicated that HSP70s …

Background Heat shock-related 70 kDa protein 2 (HSPA2) has been identified as a potential
cancer-promoting protein expressed at abnormal levels in a subset of cancers. However, its …

Abstract Heat Shock Protein Family A (Hsp70) Member 6 (HSPA6)(Online Mendelian
Inheritance in Man: 140555) belongs to the HSP70 family and is a partially conserved …

Intracellular HSP70 has been implicated as a cytoprotective protein, whereas the effect of
extracellular HSP70 on tumor cells has not been fully understood to date. Here we report …

Heat shock protein family A (HSP70) member 5 (HSPA5) is aberrantly expressed in various
tumors and closely associated with the progression and prognosis of cancer. Nevertheless …

Background/Aim: It has been shown that HSPA2 protein, a testis-enriched member of
HSPA/HSP70 family, is important for cancer cell growth and metastasis. However, the status …

Heat shock proteins (HSPs) are a large group of chaperones considered critical for
maintaining cellular proteostasis. Their aberrant expression in tumors can modulate the …

Background Hepatocellular carcinoma (HCC) is an inflammation-associated tumor involved
in immune tolerance and evasion in the immune microenvironment. Heat shock proteins …

The heat shock protein Hsp70 is crucial for regulating cellular homeostasis in stressed cells.
Although the tumorigenic potential and prognostic applications of Hsp70 have been widely …