[HTML][HTML] Therapeutic potential of microvesicles in cell therapy and regenerative medicine of ocular diseases with an especial focus on mesenchymal stem cells …

LM Rad, AV Yumashev, BM Hussen, HH Jamad… - Frontiers in …, 2022 - frontiersin.org
These days, mesenchymal stem cells (MSCs), because of immunomodulatory and pro-
angiogenic abilities, are known as inevitable factors in regenerative medicine and cell …

Therapeutic potential of mesenchymal stem cell-derived exosomes in the treatment of eye diseases

CR Harrell, B Simovic Markovic, C Fellabaum… - Cell Biology and …, 2018 - Springer
Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic
characteristics, extensively explored as new therapeutic agents in cell-based therapy of …

Mesenchymal stem cell-derived exosomes as new remedy for the treatment of inflammatory eye diseases

C RANDALL HARRELL, A Volarevic, D PAVLOVIC… - BioCell, 2022 - boris.unibe.ch
Detrimental immune response has a crucially important role in the development and
progression of inflammatory eye diseases. Inflammatory mediators and proteolytic enzymes …

[HTML][HTML] Mesenchymal stem cell-derived exosomes in ophthalmology: a comprehensive review

KY Wu, H Ahmad, G Lin, M Carbonneau, SD Tran - Pharmaceutics, 2023 - mdpi.com
Over the past decade, the field of mesenchymal stem cell (MSC) therapy has exhibited rapid
growth. Due to their regenerative, reparatory, and immunomodulatory capacities, MSCs …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles as a new therapeutic strategy for ocular diseases

B Yu, XR Li, XM Zhang - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have attracted considerable attention for their activity in the
treatment of refractory visual disorders. Since MSCs were found to possess the beneficial …

Pathological role of inflammation in ocular disease progress and its targeting by mesenchymal stem cells (MSCs) and their exosome; current status and prospect

A Nouralishahi, N Fazlinejad, RDC Pecho… - … -Research and Practice, 2023 - Elsevier
Because of their unique capacity for differentiation to a diversity of cell lineages and
immunosuppressive properties, mesenchymal stem cells (MSC) are being looked at as a …

[HTML][HTML] Mesenchymal stem cells and exosomes: A novel therapeutic approach for corneal diseases

B Bhujel, SH Oh, CM Kim, YJ Yoon, YJ Kim… - International Journal of …, 2023 - mdpi.com
The cornea, with its delicate structure, is vulnerable to damage from physical, chemical, and
genetic factors. Corneal transplantation, including penetrating and lamellar keratoplasties …

Topical ophthalmic instillation of engineered hMSCs-derived exosomes: a novel non-invasive therapeutic strategy for ocular posterior-segment disorder

H Yang, P Wu, T Wang, Y Yu, J Li, R Liu… - … and Biophysical Research …, 2024 - Elsevier
Due to the presence of protective mechanisms and blood-ocular barriers in the eye, drugs
aimed at treating posterior segment ophthalmic disorder have to be administrated mostly …

[HTML][HTML] Effects of mesenchymal stem cell-derived exosomes on experimental autoimmune uveitis

L Bai, H Shao, H Wang, Z Zhang, C Su, L Dong, B Yu… - Scientific reports, 2017 - nature.com
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …

Stem cell-derived extracellular vesicles as a potential therapeutic tool for eye diseases: from benchtop to bedside

N Attia, YH Khalifa, M Mashal, G Puras… - Cell Biology and …, 2022 - Springer
Stem cell-derived extracellular vesicles (SC-EVs) have remarkably drawn clinicians'
attention in treating ocular diseases. As a paracrine factor of stem cells and an appealing …