The different facets of dyslipidemia and hypertension in atherosclerosis

J Hurtubise, K McLellan, K Durr, O Onasanya… - Current atherosclerosis …, 2016 - Springer
Atherosclerosis is the narrowing of arteries due to the accumulation of macrophages
overloaded with lipids resulting in foam cell formation, and these events occur preferentially …

Update on lipids, inflammation and atherothrombosis

L Badimon, RF Storey, G Vilahur - Thrombosis and haemostasis, 2011 - thieme-connect.com
Atherosclerosis is an inflammatory disease that involves the arterial wall and is
characterised by the progressive accumulation of lipids in the vessel wall. The first step is …

[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis

MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …

Targeting early atherosclerosis: a focus on oxidative stress and inflammation

P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …

Inflammation in atherosclerosis: a cause or a result of vascular disorders?

I Manduteanu, M Simionescu - Journal of cellular and …, 2012 - Wiley Online Library
Sound data support the concept that in atherosclerosis, inflammation and dyslipidemia
intersect each other and that irrespective of the initiator, both participate from the early …

Hypertension and dyslipidemia: the two partners in endothelium-related crime

E Dąbrowska, K Narkiewicz - Current Atherosclerosis Reports, 2023 - Springer
Abstract Purpose of Review The goal of this article is to characterize the endothelium's role
in the development of hypertension and dyslipidemia and to point out promising therapeutic …

Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis

AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …

The pathogenesis of atherosclerosis: an overview

CJ Schwartz, AJ Valente, EA Sprague… - Clinical …, 1991 - Wiley Online Library
In this unifying hypothesis directed to the etiology and pathogenesis of atherosclerosis, the
importance of focal arterial lesion‐prone sites has been emphasized. Key initial participants …

Atherosclerosis and inflammation: overview and updates

GR Geovanini, P Libby - Clinical science, 2018 - portlandpress.com
The concept that inflammation participates pivotally in the pathogenesis of atherosclerosis
and its complications has gained considerable attention, but has not yet entered clinical …

Effects of native and modified low-density lipoproteins on monocyte recruitment in atherosclerosis

CA Gleissner, N Leitinger, K Ley - Hypertension, 2007 - Am Heart Assoc
Atherosclerosis is a chronic inflammatory disease of the arterial wall1–3 with enormous
epidemiological relevance. 4, 5 Recruitment of monocytes to the vascular wall is a key …