The placebo effect and its determinants in osteoarthritis: meta-analysis of randomised controlled trials

W Zhang, J Robertson, AC Jones, PA Dieppe… - Annals of the …, 2008 - ard.bmj.com
Objective: To examine the placebo effect and its potential determinants in the treatment of
osteoarthritis (OA) via a systematic literature search of Medline, EMBASE, Scientific Citation …

[HTML][HTML] The “placebo” response in osteoarthritis and its implications for clinical practice

M Doherty, P Dieppe - Osteoarthritis and cartilage, 2009 - Elsevier
We recently published a systematic review and meta-analysis of placebo response in
osteoarthritis (OA) randomised controlled trials (RCTs). This confirmed the appreciable effect …

Effectiveness and implications of alternative placebo treatments: a systematic review and network meta-analysis of osteoarthritis trials

RR Bannuru, TE McAlindon, MC Sullivan… - Annals of internal …, 2015 - acpjournals.org
Background: Placebo controls are essential in evaluating the effectiveness of medical
treatments. Although it is unclear whether different placebo interventions for osteoarthritis …

[PDF][PDF] The powerful placebo effect in osteoarthritis

W Zhang - Clin Exp Rheumatol, 2019 - clinexprheumatol.org
Osteoarthritis (OA) is the most common form of arthritis. Pain and its related function and
stiffness are currently the major symptoms and primary outcomes for treatment. However, the …

[HTML][HTML] Mechanisms of the placebo response in pain in osteoarthritis

A Abhishek, M Doherty - Osteoarthritis and cartilage, 2013 - Elsevier
Introduction Administration of a placebo associates with symptomatic improvement in many
conditions–the so-called placebo response. In this review we explain the concept of placebo …

The long-lasting effects of “placebo injections” in knee osteoarthritis: a meta-analysis

D Previtali, G Merli, G Di Laura Frattura… - Cartilage, 2021 - journals.sagepub.com
Objectives To quantify the placebo effect of intraarticular injections for knee osteoarthritis in
terms of pain, function, and objective outcomes. Factors influencing placebo effect were …

Is the placebo powerless? Update of a systematic review with 52 new randomized trials comparing placebo with no treatment

A Hróbjartsson, PC Gøtzsche - Journal of internal medicine, 2004 - Wiley Online Library
Background. It is widely believed that placebo interventions induce powerful effects. We
could not confirm this in a systematic review of 114 randomized trials that compared placebo …

Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials

K Meissner, H Distel, U Mitzdorf - BMC medicine, 2007 - Springer
Background Recent reviews on placebo effects in clinical trials suggest that objective
changes following placebo treatments may not exist or, at least, have been considerably …

Is the placebo powerless? An analysis of clinical trials comparing placebo with no treatment

A Hróbjartsson, PC Gøtzsche - New England Journal of Medicine, 2001 - Mass Medical Soc
Background Placebo treatments have been reported to help patients with many diseases,
but the quality of the evidence supporting this finding has not been rigorously evaluated …

The paradox of sham therapy and placebo effect in osteopathy: a systematic review

F Cerritelli, M Verzella, L Cicchitti, G D'Alessandro… - Medicine, 2016 - journals.lww.com
Background: Placebo, defined as “false treatment,” is a common gold-standard method to
assess the validity of a therapy both in pharmacological trials and manual medicine …