Tumour angiogenesis is a fast growing domain in tumour biology. Many growth factors and
mechanisms have been unravelled. For almost 30 years, the sprouting of new vessels out of …

Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …

Robust neovascularization and lymphangiogenesis have been found in a variety of
aggressive and metastatic tumors. Endothelial sprouting angiogenesis is generally …

Angiogenesis is a term that describes the formation of new blood and lymphatic vessels from
a pre-existing vasculature. This allows tumour cells to acquire sustenance in the form of …

Cancer cells can use existing blood vessels to acquire a vasculature. This process is termed
'vessel co-option'. Vessel co-option is an alternative to the growth of new blood vessels, or …

Tumor angiogenesis is a fast growing sub-domain of angiogenesis research and tumor
biology. Basic mechanisms have been unraveled and many key players identified. For many …

Solid tumour growth is dependent on the development of an adequate blood supply. For
years, sprouting angiogenesis has been considered an exclusive mechanism of tumour …

How Do Tumors Recruit Blood Vessels? Blood vessels are indispensible for tumor growth
and metastasis. Hence, tumors exploit multiple avenues to recruit blood vessels …

Etiological concepts on cancer development, malignant growth and tumour propagation
have undergone a revolutionary development during recent years: Among other aspects, the …

Angiogenesis is a crucial event in the physiological processes of embryogenesis and wound
healing. During malignant transformation, dysregulation of angiogenesis leads to the …