Primary airway epithelial cells (pAECs) cultivated at air-liquid interface (ALI) conditions are
widely used as surrogates for human in vivo epithelia. To extend the proliferative capacity …

Primary airway epithelial cells (pAECs) cultivated at air-liquid interface (ALI) conditions are
widely used as surrogates for human in vivo epithelia. To extend the proliferative capacity …

Primary airway epithelial cells (pAEC) cultivated at air‐liquid interface (ALI) conditions are
widely 25 used as surrogates for human in vivo epithelia. To extend the proliferative capacity …

Primary differentiated human epithelial cell cultures have been widely used by researchers
to study viral fitness and virus-host interactions, especially during the COVID19 pandemic …

The nasal epithelium lining the human upper airway is the primary portal of entry for several
respiratory pathogens, including the recently emerged SARS-CoV-2 virus responsible for …

The global urgency to uncover medical countermeasures to combat the COVID-19
pandemic caused by the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) …

The dynamics of SARS-CoV-2 infection in COVID-19 patients are highly variable, with a
subset of patients demonstrating prolonged virus shedding, which poses a significant …

Abstract Development of an anti-SARS-CoV-2 therapeutic is hindered by the lack of
physiologically relevant model systems that can recapitulate host-viral interactions in human …

Airway-liquid interface cultures of primary epithelial cells and of induced pluripotent stem
cell-derived airway epithelial cells (ALI and iALI, respectively) are physiologically relevant …

The human airway mucociliary epithelium can be recapitulated in vitro using primary cells
cultured in an Air-Liquid Interface (ALI), a reliable surrogate to perform pathophysiological …