[HTML][HTML] The therapeutic potential of psilocybin

H Lowe, N Toyang, B Steele, H Valentine, J Grant, A Ali… - Molecules, 2021 - mdpi.com
The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …

Psilocybin: From ancient magic to modern medicine

DE Nichols - The Journal of antibiotics, 2020 - nature.com
Abstract Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) is an indole-based
secondary metabolite produced by numerous species of mushrooms. South American Aztec …

[HTML][HTML] Potential therapeutic effects of psilocybin

MW Johnson, RR Griffiths - Neurotherapeutics, 2017 - Springer
Psilocybin and other 5-hydroxytryptamine 2A agonist classic psychedelics have been used
for centuries as sacraments within indigenous cultures. In the mid-twentieth century they …

DARK classics in chemical neuroscience: psilocybin

HA Geiger, MG Wurst, RN Daniels - ACS chemical Neuroscience, 2018 - ACS Publications
Psilocybin is found in a family of mushrooms commonly known as “magic mushrooms” that
have been used throughout history to induce hallucinations. In the late 1950s Albert …

The therapeutic potential of psilocybin: a systematic review

J van Amsterdam, W van den Brink - Expert opinion on drug safety, 2022 - Taylor & Francis
Introduction Psychedelic drugs were used quite extensively before their prohibition in 1968
which delayed research. However, since the 1990s, studies on the potential therapeutic …

[PDF][PDF] Analysis of psilocybin-assisted therapy in medicine: A narrative review

S Ziff, B Stern, G Lewis, M Majeed, VR Gorantla - Cureus, 2022 - cureus.com
Psilocybin-containing mushrooms have been consumed by various cultures in many
different parts of the world for thousands of years. Psilocybin, a classic psychedelic, contains …

The pharmacology of psilocybin

T Passie, J Seifert, U Schneider, HM Emrich - Addiction biology, 2002 - Wiley Online Library
Abstract Psilocybin (4‐phosphoryloxy‐N, N‐dimethyltryptamine) is the major psychoactive
alkaloid of some species of mushrooms distributed worldwide. These mushrooms represent …

[HTML][HTML] Therapeutic use of psilocybin: Practical considerations for dosing and administration

CA MacCallum, LA Lo, CA Pistawka, JK Deol - Frontiers in Psychiatry, 2022 - frontiersin.org
The interest in psilocybin as a therapeutic approach has grown exponentially in recent
years. Despite increasing access, there remains a lack of practical guidance on the topic for …

Investigation of the structure–activity relationships of psilocybin analogues

AK Klein, M Chatha, LJ Laskowski… - ACS pharmacology & …, 2020 - ACS Publications
The 5-HT2A receptor is thought to be the primary target for psilocybin (4-phosphoryloxy-N, N-
dimethyltryptamine) and other serotonergic hallucinogens (psychedelic drugs). Although a …

Psilocybin-assisted therapy: A review of a novel treatment for psychiatric disorders

K Thomas, B Malcolm, D Lastra - Journal of Psychoactive Drugs, 2017 - Taylor & Francis
Recent research suggests that functional connectivity changes may be involved in the
pathophysiology of psychiatric disorders. Hyperconnectivity in the default mode network has …