[HTML][HTML] Amino-pyrazoles in medicinal chemistry: A review
M Lusardi, A Spallarossa, C Brullo - International journal of molecular …, 2023 - mdpi.com
A pyrazole nucleus is an easy-to-prepare scaffold with large therapeutic potential.
Consequently, the search for new pyrazole-based compounds is of great interest to the …
Consequently, the search for new pyrazole-based compounds is of great interest to the …
5-Amino-pyrazoles: potent reagents in organic and medicinal synthesis
Amino-pyrazoles have proven to be a class of fascinating and privileged organic tools for the
construction of diverse heterocyclic or fused heterocyclic scaffolds. This review presents …
construction of diverse heterocyclic or fused heterocyclic scaffolds. This review presents …
Recently reported biological activities of pyrazole compounds
JV Faria, PF Vegi, AGC Miguita, MS Dos Santos… - Bioorganic & medicinal …, 2017 - Elsevier
The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms.
Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved …
Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved …
The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review.
Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
combinatorial as well as medicinal chemistry. This review presents a detailed overview on …
Recent advances in bioactive pyrazoles
ŞG Küçükgüzel, S Şenkardeş - European Journal of Medicinal Chemistry, 2015 - Elsevier
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …
have been investigated in the development of novel compounds with hypoglycemic …
Biologically active pyrazole derivatives
Nitrogen-containing heterocyclic compounds and their derivatives have historically been
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …
invaluable as a source of therapeutic agents. Pyrazole, which has two nitrogen atoms and …
[HTML][HTML] Synthesis and pharmacological activities of pyrazole derivatives: A review
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
that possesses almost all types of pharmacological activities. The presence of this nucleus in …
[HTML][HTML] Evaluation of substituted pyrazole-based kinase inhibitors in one decade (2011–2020): Current status and future prospects
Pyrazole has been recognized as a pharmacologically important privileged scaffold whose
derivatives produce almost all types of pharmacological activities and have attracted much …
derivatives produce almost all types of pharmacological activities and have attracted much …
4,5-Dihydro-1H-pyrazole: an indispensable scaffold
JM Alex, R Kumar - Journal of enzyme inhibition and medicinal …, 2014 - Taylor & Francis
Pyrazoles, categorized as nitrogen-containing heterocycles, are well known for their
interminable participation in the field of perpetual research and development of …
interminable participation in the field of perpetual research and development of …
Pyrazole containing natural products: Synthetic preview and biological significance
A large number of structurally diverse natural compounds containing azole nucleus
constitute an important class of biologically active heterocycles that are gaining more …
constitute an important class of biologically active heterocycles that are gaining more …