Aspirin-free strategies in cardiovascular disease and cardioembolic stroke prevention

D Capodanno, R Mehran, M Valgimigli… - Nature Reviews …, 2018 - nature.com
In patients with manifestations of cardiovascular disease, acetylsalicylic acid (popularly
known as aspirin) has been the mainstay of treatment for decades owing to its capacity to …

The role of aspirin for stroke prevention in atrial fibrillation

GYH Lip - Nature Reviews Cardiology, 2011 - nature.com
Atrial fibrillation (AF) is a major cause of stroke and thromboembolism, resulting in
substantial morbidity and mortality. For the majority of patients with AF, aspirin has a limited …

[PDF][PDF] Update on aspirin in the treatment and prevention of cardiovascular disease

CH Hennekens - American Journal of Managed Care, 2002 - ajmc.s3.amazonaws.com
Antiplatelet therapy, most notably aspirin, has been well documented to reduce risks of
subsequent cardiovascular disease (CVD) in secondary prevention, acute myocardial …

Clinical use of aspirin in treatment and prevention of cardiovascular disease

Y Dai, J Ge - Thrombosis, 2012 - Wiley Online Library
Cardiovascular disease (CVD), principally heart disease and stroke, is the leading cause of
death for both males and females in developed countries. Aspirin is the most widely used …

Aspirin for the prevention of cardiovascular events in patients without clinical cardiovascular disease: a meta-analysis of randomized trials

JS Berger, A Lala, MJ Krantz, GS Baker, WR Hiatt - American heart journal, 2011 - Elsevier
Background The benefit of aspirin to prevent cardiovascular events in subjects without
clinical cardiovascular disease relative to the increased risk of bleeding is uncertain …

Risk of hemorrhagic stroke with aspirin use: an update

PB Gorelick, SM Weisman - Stroke, 2005 - Am Heart Assoc
Background—Low-dose aspirin is an important therapeutic option in the secondary
prevention of myocardial infarction (MI) and ischemic stroke, especially in light of its unique …

Low-dose aspirin for the prevention of atherothrombosis

C Patrono, LA García Rodríguez… - … England Journal of …, 2005 - Mass Medical Soc
This review considers the role of low-dose aspirin for the prevention of atherothrombosis,
discussing the molecular mechanism of action of aspirin as well as clinical and …

Aspirin, 110 years later

C Patrono, B Rocca - Journal of Thrombosis and Haemostasis, 2009 - Wiley Online Library
Although conceived at the end of the 19th century as a synthetic analgesic agent with
improved gastric tolerability vs. naturally occurring salicylates, acetylsalicylic acid (marketed …

Efficacy and safety of aspirin for primary prevention of cardiovascular events: a meta-analysis and trial sequential analysis of randomized controlled trials

AN Mahmoud, MM Gad, AY Elgendy… - European heart …, 2019 - academic.oup.com
Aims The role of aspirin in the primary prevention setting is continuously evolving. Recent
randomized trials have challenged the role of aspirin in the primary prevention setting …

Aspirin for the primary prevention of cardiovascular disease: time for a platelet-guided approach

LB Cofer, TJ Barrett, JS Berger - Arteriosclerosis, Thrombosis, and …, 2022 - Am Heart Assoc
Aspirin protects against atherothrombosis while increasing the risk of major bleeding.
Although it is widely used to prevent cardiovascular disease (CVD), its benefit does not …