Steatotic liver disease (SLD) is a burgeoning health problem predominantly associated with
excessive alcohol consumption, which causes alcohol-related liver disease (ALD), and high …

Background & Aims Nonalcoholic fatty liver disease is highly associated with obesity and
progresses to nonalcoholic steatohepatitis when the liver develops overt inflammatory …

Secretory pathway dysfunction and lipid accumulation (steatosis) are the two most common
responses of hepatocytes to ethanol exposure and are major factors in the pathophysiology …

To overcome the rising burdens of nonalcoholic fatty liver disease, mechanistic linkages in
mitochondrial dysfunction, inflammation and hepatic injury are critical. As ataxia …

We investigated the progression of nonalcoholic fatty liver disease from fatty liver to
steatohepatitis using single-nucleus and bulk ATAC-seq on the livers of rats fed a high-fat …

Aim Nonalcoholic fatty liver disease (NAFLD) has become a global epidemic, but its
pathogenesis is unclear. STEAP4, a member of six transmembrane protein family, integrates …

Simple Summary Alcohol-associated liver disease (ALD) is a global health problem with
high morbidity and mortality. ALD is a multifactorial disease which manifests as lipid …

Chronic alcoholic liver disease has brought great harm to human health. Alcoholic fatty liver
disease is the first stage in the progression of all chronic alcoholic liver diseases. At present …

Nonalcoholic fatty liver disease (NAFLD) has emerged globally and is associated with
inflammatory signaling. The underlying mechanisms remain poorly delineated, although …

Non-alcoholic steatotic liver disease (NAFLD) is the most common cause of chronic liver
disease worldwide. NAFLD has a major effect on the intrinsic proliferative properties of …