IL-2-mediated CD4 T-cell activation correlates highly with effective serological and T-cell responses to SARS-CoV-2 vaccination in people living with HIV (PLWH)

A Gupta, E Righi, A Konnova, C Sciammarella… - medRxiv, 2024 - medrxiv.org
People living with HIV (PLWH) despite having appreciable depletion of CD4+ T-cell show a
good SARS-CoV-2 vaccination response. The underlying mechanism (s) are currently not …

[HTML][HTML] Impact of SARS-CoV-2 vaccination on systemic immune responses in people living with HIV

C Bessen, C Plaza-Sirvent, A Simsek, J Bhat… - Frontiers in …, 2022 - frontiersin.org
Despite the development of vaccines, which protect healthy people from severe and life-
threatening Covid-19, the immunological responses of people with secondary …

[HTML][HTML] SARS-CoV-2 Vaccine-induced T-cell response after three doses in people living with HIV on antiretroviral therapy compared to seronegative controls (CTN …

Y Alexandrova, A Yero, RS Mboumba Bouassa… - Viruses, 2023 - mdpi.com
People living with HIV (PLWH) may be at risk for poor immunogenicity to certain vaccines,
including the ability to develop immunological memory. Here, we assessed T-cell …

[HTML][HTML] Characterization of humoral and SARS-CoV-2 specific T cell responses in people living with HIV

A Alrubayyi, E Gea-Mallorquí, E Touizer… - Nature …, 2021 - nature.com
There is an urgent need to understand the nature of immune responses against SARS-CoV-
2, to inform risk-mitigation strategies for people living with HIV (PLWH). Here we show that …

T-Cell Responses to COVID-19 Vaccines and Breakthrough Infection in People Living with HIV Receiving Antiretroviral Therapy

S Datwani, R Kalikawe, R Waterworth, FM Mwimanzi… - Viruses, 2024 - mdpi.com
People living with HIV (PLWH) can exhibit impaired immune responses to vaccines.
Accumulating evidence indicates that PLWH, particularly those receiving antiretroviral …

[HTML][HTML] A third (booster) dose of the inactivated SARS-CoV-2 vaccine elicits immunogenicity and T follicular helper cell responses in people living with HIV

Z Lv, S Lv, Q Li, Y Xia, Z Feng, H Zhang… - Frontiers in …, 2023 - frontiersin.org
Introduction This study sought to explore the immunogenicity of a booster dose of an
inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine in …

Robust vaccine-induced as well as hybrid B-and T-cell immunity across SARS-CoV-2 vaccine platforms in people with HIV

ML Verburgh, L van Pul, M Grobben, A Boyd… - Microbiology …, 2023 - Am Soc Microbiol
Few studies have comprehensively compared severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) vaccine-induced and hybrid B-and T-cell responses in people …

HIV infection alters SARS-CoV-2 responsive immune parameters but not clinical outcomes in COVID-19 disease

F Karim, I Gazy, S Cele, Y Zungu, R Krause… - MedRxiv, 2020 - medrxiv.org
HIV infection alters the immune response and can compromise protective immunity to
multiple pathogens following vaccination. We investigated the impact of HIV on the immune …

SARS-CoV-2 Humoral and Cellular Immune Responses in HIV-Positive Patients

S Ruta, CP Popescu, L Matei, C Grancea, AM Paun… - 2024 - preprints.org
Immunosuppressed individuals, such as people living with HIV (PLWH), remain vulnerable
to severe COVID-19. We analyzed the persistence of specific SARS-CoV-2 humoral and …

[HTML][HTML] Immunologic interplay between HIV/AIDS and COVID-19: adding fuel to the flames?

M Augello, V Bono, R Rovito, C Tincati… - Current HIV/AIDS …, 2023 - Springer
Abstract Purpose of Review HIV/AIDS and COVID-19 have been the major pandemics
overwhelming our times. Given the enduring immune disfunction featuring people living with …