The canonical double-helix form of DNA is thought to predominate both in dilute solution
and in living cells. Sequence-dependent fluctuations in local DNA shape occur within the …

We previously used a pattern recognition program for nucleic acids to detect sequences with
the potential to form intrastrand triplexes. Potential intrastrand triplex (PIT) element families …

The ability of DNA to exist in configurations other than its classical double-stranded form has
been known for many years. There has been a spectacular recent surge of interest in these …

Formation of natural intramolecular triple-helical structures of DNA is still an intriguing
research topic in view of the possible involvement of these structures in biological …

Revised Manuscript Received November 12, 1992 abstract: Recent experimental studies of
the structure of triple helices show that their conformation in solution differs from the A-like …

A detailed kinetic study of triple helix formation was performed by surface plasmon
resonance. Three systems were investigated involving 15mer pyrimidine oligonucleotides …

The ability of double-stranded DNA to form a triple-helical structure by hydrogen bonding
with a third strand is well established, but the biological functions of these structures remain …

Nucleic acid triple helices have provoked interest since their discovery more than 40 years
ago, but it remains unknown whether such structures occur naturally in cells. To pursue this …

Certain DNA sequences, including mirror-symmetric polypyrimidine• polypurine runs, are
capable of folding into a triple-helix–containing non–B-form DNA structure called H-DNA …

Research concerning oligonucleotide-directed triple helix formation has mainly focused on
the binding of DNA oligonucleotides to duplex DNA. The participation of RNA strands In …