Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …

CD8+ T cells responding to chronic infection adapt an altered differentiation program that
provides some restraint on pathogen replication yet limits immunopathology. This adaptation …

How chemokines shape the immune response to viral infection of the central nervous
system (CNS) has largely been considered within the context of recruitment and activation of …

Chemokine (C–C motif) ligand 19 (CCL19) is a critical regulator of the induction of T cell
activation, immune tolerance, and inflammatory responses during continuous immune …

CXCR4 and its ligand CXCL12 mediate the homing of progenitor cells in the bone marrow
and their recruitment to sites of injury, as well as affect processes such as cell arrest …

Chemokines (chemotactic cytokines) are involved in a wide variety of biological processes.
Following microbial infection, there is often robust chemokine signaling elicited from infected …

Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …

Recruitment and activation of leukocytes are important for elimination of microbes, including
viruses, from infected areas. Chemokines constitute a group of bioactive peptides that …

C–X–C motif chemokine 10 (CXCL10) also known as interferon γ-induced protein 10kDa (IP-
10) or small-inducible cytokine B10 is a cytokine belonging to the CXC chemokine family …

CD8+ T cells play a critical role in limiting peripheral virus replication, yet how they locate
virus-infected cells within tissues is unknown. Here, we have examined the environmental …