The tale of SOX2: Focusing on lncRNA regulation in cancer progression and therapy
P Huang, F Wen, YS Li, Q Li - Life Sciences, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have emerged as influential contributors to diverse
cellular processes, which regulate gene function and expression via multiple mechanistic …
cellular processes, which regulate gene function and expression via multiple mechanistic …
SOX4: epigenetic regulation and role in tumorigenesis
Sex-determining region Y-related (SRY) high-mobility group box 4 (SOX4) is a member of
the group C subfamily of SOX transcription factors and promotes tumorigenesis by endowing …
the group C subfamily of SOX transcription factors and promotes tumorigenesis by endowing …
A novel lncRNA SOX2OT promotes the malignancy of human colorectal cancer by interacting with miR-194-5p/SOX5 axis
Y Feng, Y Xu, Y Gao, Y Chen, X Wang, Z Chen - Cell Death & Disease, 2021 - nature.com
Long noncoding RNAs (lncRNAs) show emerging roles in colorectal cancer (CRC)
development and are considered to be involved in the potential mechanism of tumor …
development and are considered to be involved in the potential mechanism of tumor …
[HTML][HTML] The dark side of SOX2: cancer-a comprehensive overview
EL Wuebben, A Rizzino - Oncotarget, 2017 - ncbi.nlm.nih.gov
The pluripotency-associated transcription factor SOX2 is essential during mammalian
embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over …
embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over …
Long non-coding RNA SOX2OT: expression signature, splicing patterns, and emerging roles in pluripotency and tumorigenesis
SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA which harbors one of the
major regulators of pluripotency, SOX2 gene, in its intronic region. SOX2OT gene is mapped …
major regulators of pluripotency, SOX2 gene, in its intronic region. SOX2OT gene is mapped …
Long noncoding RNA lnc-sox5 modulates CRC tumorigenesis by unbalancing tumor microenvironment
ABSTRACT Long non-coding RNAs (LncRNAs) have been recently regarded as systemic
regulators in multiple biologic processes including tumorigenesis. In this study, we observed …
regulators in multiple biologic processes including tumorigenesis. In this study, we observed …
LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2
X Chang, H Zhang, Q Yang, L Pang - Cell Cycle, 2020 - Taylor & Francis
Long non-coding RNA (lncRNA) SOX2 overlapping transcript (SOX2OT) has been shown to
play an oncogenic role in diverse cancers, generating eight transcript variants. SOX2 is …
play an oncogenic role in diverse cancers, generating eight transcript variants. SOX2 is …
[HTML][HTML] SOX2OT, a novel tumor-related long non-coding RNA
Y Wang, N Wu, X Luo, X Zhang, Q Liao… - Biomedicine & …, 2020 - Elsevier
SOX2OT is a long non-coding RNA that is highly expressed in embryonic stem cells. The
SOX2OT gene is comprised of 10 exons and more than two transcription start sites …
SOX2OT gene is comprised of 10 exons and more than two transcription start sites …
LncSOX4 serves an oncogenic role in the tumorigenesis of epithelial ovarian cancer by promoting cell proliferation and inhibiting apoptosis
Y Liu, Y Wang, D Yao, D Cui - Molecular Medicine …, 2018 - spandidos-publications.com
Epithelial ovarian cancer is one of the primary causes of gynecological cancer mortality.
Increasing evidence has suggested that long non‑coding RNAs (lncRNAs) may serve a …
Increasing evidence has suggested that long non‑coding RNAs (lncRNAs) may serve a …
Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer
M Saghaeian Jazi, NM Samaei, M Ghanei… - Tumor Biology, 2016 - Springer
Despite the advances in cancer therapy, lung cancer still remains the most leading cause of
cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as …
cancer death worldwide. The long non-coding RNAs (lncRNAs) are recently introduced as …