Pulmonary drug delivery by powder aerosols

MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …

How can we bring high drug doses to the lung?

S Claus, C Weiler, J Schiewe, W Friess - European Journal of …, 2014 - Elsevier
In the last decades, dry powder inhalation has become a very attractive option for pulmonary
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …

Dry powder formulations for pulmonary delivery

RJ Malcolmson, JK Embleton - Pharmaceutical Science & Technology …, 1998 - Elsevier
This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …

Dry powder inhalers for pulmonary drug delivery

HW Frijlink, AH De Boer - Expert opinion on drug delivery, 2004 - Taylor & Francis
The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …

Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers

N Islam, MJ Cleary - Medical engineering & physics, 2012 - Elsevier
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …

Drug delivery to the respiratory tract using dry powder inhalers

MP Timsina, GP Martin, C Marriott, D Ganderton… - International journal of …, 1994 - Elsevier
The inhalation of aerosolised drug has become a well established treatment modality in
conditions such as asthma. The pressurised metered-dose inhaler (MDI) is still the most …

Dry powder inhalers: an overview

PJ Atkins - Respiratory care, 2005 - rc.rcjournal.com
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly
in Europe, where they currently are used by a large number of patients for the delivery of …

[HTML][HTML] Devices for dry powder drug delivery to the lung

K Berkenfeld, A Lamprecht, JT McConville - Aaps Pharmscitech, 2015 - Springer
Dry powder inhalers (DPIs) are an important and increasingly investigated method of
modern therapy for a growing number of respiratory diseases. DPIs are a promising option …

[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review

B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …

[HTML][HTML] Challenges for pulmonary delivery of high powder doses

I Sibum, P Hagedoorn, AH de Boer, HW Frijlink… - International journal of …, 2018 - Elsevier
In recent years there is an increasing interest in the pulmonary delivery of large cohesive
powder doses, ie drugs with a low potency such as antibiotics or drugs with a high potency …