Pulmonary drug delivery by powder aerosols
MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
How can we bring high drug doses to the lung?
S Claus, C Weiler, J Schiewe, W Friess - European Journal of …, 2014 - Elsevier
In the last decades, dry powder inhalation has become a very attractive option for pulmonary
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …
drug delivery to treat lung diseases like cystic fibroses and lung infections. In contrast to the …
Dry powder formulations for pulmonary delivery
RJ Malcolmson, JK Embleton - Pharmaceutical Science & Technology …, 1998 - Elsevier
This review examines the key issues surrounding the development and preparation of
formulations for dry powder inhalers. The various inhaler devices that are currently available …
formulations for dry powder inhalers. The various inhaler devices that are currently available …
Dry powder inhalers for pulmonary drug delivery
HW Frijlink, AH De Boer - Expert opinion on drug delivery, 2004 - Taylor & Francis
The pulmonary route is an interesting route for drug administration, both for effective local
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …
therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the …
Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …
great potential to produce maximum therapeutic benefit. Among the available options the dry …
Drug delivery to the respiratory tract using dry powder inhalers
MP Timsina, GP Martin, C Marriott, D Ganderton… - International journal of …, 1994 - Elsevier
The inhalation of aerosolised drug has become a well established treatment modality in
conditions such as asthma. The pressurised metered-dose inhaler (MDI) is still the most …
conditions such as asthma. The pressurised metered-dose inhaler (MDI) is still the most …
Dry powder inhalers: an overview
PJ Atkins - Respiratory care, 2005 - rc.rcjournal.com
Dry powder inhalers (DPIs) are a widely accepted inhaled delivery dosage form, particularly
in Europe, where they currently are used by a large number of patients for the delivery of …
in Europe, where they currently are used by a large number of patients for the delivery of …
[HTML][HTML] Devices for dry powder drug delivery to the lung
K Berkenfeld, A Lamprecht, JT McConville - Aaps Pharmscitech, 2015 - Springer
Dry powder inhalers (DPIs) are an important and increasingly investigated method of
modern therapy for a growing number of respiratory diseases. DPIs are a promising option …
modern therapy for a growing number of respiratory diseases. DPIs are a promising option …
[HTML][HTML] Dry powder for pulmonary delivery: A comprehensive review
B Chaurasiya, YY Zhao - Pharmaceutics, 2021 - mdpi.com
The pulmonary route has long been used for drug administration for both local and systemic
treatment. It possesses several advantages, which can be categorized into physiological, ie …
treatment. It possesses several advantages, which can be categorized into physiological, ie …
[HTML][HTML] Challenges for pulmonary delivery of high powder doses
I Sibum, P Hagedoorn, AH de Boer, HW Frijlink… - International journal of …, 2018 - Elsevier
In recent years there is an increasing interest in the pulmonary delivery of large cohesive
powder doses, ie drugs with a low potency such as antibiotics or drugs with a high potency …
powder doses, ie drugs with a low potency such as antibiotics or drugs with a high potency …