[HTML][HTML] Manipulating resident microbiota to enhance regulatory immune function to treat inflammatory bowel diseases

Y Mishima, RB Sartor - Journal of gastroenterology, 2020 - Springer
Altered intestinal microbial composition (dysbiosis) and metabolic products activate
aggressive mucosal immune responses that mediate inflammatory bowel diseases (IBD) …

[HTML][HTML] The role of gut microbiota biomodulators on mucosal immunity and intestinal inflammation

C Amoroso, F Perillo, F Strati, M Fantini, F Caprioli… - Cells, 2020 - mdpi.com
Alterations of the gut microbiota may cause dysregulated mucosal immune responses
leading to the onset of inflammatory bowel diseases (IBD) in genetically susceptible hosts …

Microbial-based and microbial-targeted therapies for inflammatory bowel diseases

A Oka, RB Sartor - Digestive diseases and sciences, 2020 - Springer
Inflammatory bowel diseases (IBD), including Crohn's disease, ulcerative colitis, and
pouchitis, are chronic, relapsing intestinal inflammatory disorders mediated by dysregulated …

Recent advances in gut microbiota mediated therapeutic targets in inflammatory bowel diseases: emerging modalities for future pharmacological implications

M Shamoon, NM Martin, CL O'Brien - Pharmacological Research, 2019 - Elsevier
The inflammatory bowel diseases (IBDs) are chronic inflammatory conditions, which are
increasing in prevalence worldwide. The IBDs are thought to result from an aberrant immune …

Targeting the gut microbiota in inflammatory bowel diseases: where are we?

N Benech, H Sokol - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•IBD is characterized by a vicious circle between altered host and microbiota
factors.•The gut microbiota is identified as a new therapeutic and diagnostic …

Current understanding of microbiota-and dietary-therapies for treating inflammatory bowel disease

T Eom, YS Kim, CH Choi, MJ Sadowsky, T Unno - Journal of Microbiology, 2018 - Springer
Inflammatory bowel disease (IBD) is a result of chronic inflammation caused, in some part,
by dysbiosis of intestinal microbiota, mainly commensal bacteria. Gut dysbiosis can be …

IBD and the gut microbiota—from bench to personalized medicine

E Bellaguarda, EB Chang - Current gastroenterology reports, 2015 - Springer
Inflammatory bowel diseases (IBD) are chronic relapsing inflammatory disorders involving
the gastrointestinal (GI) tract, which arise from the confluence of genetic, immunological …

[HTML][HTML] Gut microbiota in pathophysiology, diagnosis, and therapeutics of inflammatory bowel disease

H Pandey, D Jain, DWT Tang, SH Wong… - Intestinal Research, 2024 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a multifactorial disease, which is thought to be an
interplay between genetic, environment, microbiota, and immune-mediated factors …

Aetiology of inflammatory bowel disease (IBD): role of intestinal microbiota and gut-associated lymphoid tissue immune response

OC Thompson-Chagoyán, J Maldonado, A Gil - Clinical Nutrition, 2005 - Elsevier
The aetiology of inflammatory bowel disease (IBD) probably involves a combination of
genetic predisposition and environmental factors that may be channelled through an …

Current insights on the roles of gut microbiota in inflammatory bowel disease-associated extra-intestinal manifestations: Pathophysiology and therapeutic targets

Y Tie, Y Huang, R Chen, L Li, M Chen, S Zhang - Gut Microbes, 2023 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic, recurrent inflammatory disease of the
gastrointestinal tract. In addition to digestive symptoms, patients with IBD may also develop …