Single-cell Atlas of common variable immunodeficiency shows germinal center-associated epigenetic dysregulation in B-cell responses
Common variable immunodeficiency (CVID), the most prevalent symptomatic primary
immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody …
immunodeficiency, displays impaired terminal B-cell differentiation and defective antibody …
Members of the regulatory lymphocyte club in common variable immunodeficiency
S Gupta, Y Demirdag, AA Gupta - Frontiers in Immunology, 2022 - frontiersin.org
The role of CD4 T regulatory cells is well established in peripheral tolerance and the
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …
pathogenesis of the murine model and human autoimmune diseases. CD4 T regulatory cells …
Monozygotic twins discordant for common variable immunodeficiency reveal impaired DNA demethylation during naive-to-memory B-cell transition
VC Rodríguez-Cortez, L del Pino-Molina… - Nature …, 2015 - nature.com
Common variable immunodeficiency (CVID), the most frequent primary immunodeficiency
characterized by loss of B-cell function, depends partly on genetic defects, and epigenetic …
characterized by loss of B-cell function, depends partly on genetic defects, and epigenetic …
Perspectives on common variable immune deficiency
JH Park, ES Resnick… - Annals of the New …, 2011 - Wiley Online Library
Common variable immunodeficiency (CVID) is considered to be a collection of genetic
immune defects with complex inheritance patterns. While the main phenotype is loss of B …
immune defects with complex inheritance patterns. While the main phenotype is loss of B …
IgH sequences in common variable immune deficiency reveal altered B cell development and selection
Common variable immune deficiency (CVID) is the most common symptomatic primary
immune deficiency, affecting~ 1 in 25,000 persons. These patients suffer from impaired …
immune deficiency, affecting~ 1 in 25,000 persons. These patients suffer from impaired …
Impaired CpG demethylation in common variable immunodeficiency associates with B cell phenotype and proliferation rate
L del Pino-Molina, J Rodríguez-Ubreva… - Frontiers in …, 2019 - frontiersin.org
Common Variable Immunodeficiency (CVID) is characterized by impaired antibody
production and poor terminal differentiation of the B cell compartment, yet its pathogenesis is …
production and poor terminal differentiation of the B cell compartment, yet its pathogenesis is …
Understanding the genetic and epigenetic basis of common variable immunodeficiency disorder through omics approaches
Background Common variable immunodeficiency disorder (CVID) is the most frequently
encountered symptomatic primary immunodeficiency, characterized by highly …
encountered symptomatic primary immunodeficiency, characterized by highly …
Seeking relevant biomarkers in common variable immunodeficiency
H Ho, C Cunningham-Rundles - Frontiers in Immunology, 2022 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic form of
primary immunodeficiency. More than 50% of patients in some series suffer from …
primary immunodeficiency. More than 50% of patients in some series suffer from …
B-cell defects in common variable immunodeficiency: BCR signaling, protein clustering and hardwired gene mutations
AAJM van de Ven, EB Compeer… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
Common variable immunodeficiency (CVID) is the most frequently diagnosed symptomatic
primary immunodeficiency. CVID develops as a consequence of absence or malfunction of …
primary immunodeficiency. CVID develops as a consequence of absence or malfunction of …
Current understanding and recent developments in common variable immunodeficiency associated autoimmunity
JD Gereige, PJ Maglione - Frontiers in immunology, 2019 - frontiersin.org
Common variable immunodeficiency (CVID) is the most prevalent symptomatic primary
immunodeficiency and comprises a group of disorders with similar antibody deficiency but a …
immunodeficiency and comprises a group of disorders with similar antibody deficiency but a …