Although strong genetic determinants of multiple sclerosis (MS) exist, the findings of
migration studies support a role for environmental factors in this disease. Through rigorous …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) cases within
families, the changes in MS risk that occur with migration can be explained only by changes …

As discussed in Part I of this review, the geographic distribution of multiple sclerosis (MS)
and the change in risk among migrants provide compelling evidence for the existence of …

Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system.
Although its cause is not known, genetic and environmental factors both influence …

Multiple sclerosis (MS) is a highly debilitating immune mediated disorder of the central
nervous system and represents a substantial burden to the developed world. Despite the …

Lifestyle and environmental factors potently influence the risk of multiple sclerosis (MS),
because genetic predisposition only explains a fraction of the risk increase. There is strong …

Multiple sclerosis (MS) is a chronic disabling disease of the central nervous system
commonly affecting young adults. Pathologically, there are patches of inflammation …

Introduction Environmental factors play a significant role in the pathogenesis and
progression of multiple sclerosis (MS), either acting alone or by interacting with other …