Utility of peripheral blood dual color, double fusion fluorescent in situ hybridization for BCR/ABL fusion to assess cytogenetic remission status in chronic myeloid …
AP Landstrom, RP Ketterling, RA Knudson… - Leukemia & …, 2006 - Taylor & Francis
The molecular signature of BCR-ABL fusion in chronic myeloid leukemia (CML) provides a
unique tool for diagnosis and monitoring of tumor burden during therapy. The gold standard …
unique tool for diagnosis and monitoring of tumor burden during therapy. The gold standard …
Efficiency of interphase fluorescence in situ hybridization for BCR/ABL on peripheral blood smears for monitoring of CML patients: a comparison with bone marrow …
S Akel, A Kolialexi, A Mavrou… - Clinical & Laboratory …, 2002 - Wiley Online Library
Conventional cytogenetic analysis (CCA) is the standard method for monitoring of the
Philadelphia (Ph) chromosome in chronic myeloid leukemia (CML). Evaluation of breakpoint …
Philadelphia (Ph) chromosome in chronic myeloid leukemia (CML). Evaluation of breakpoint …
Qualitative and Quantitative Evaluation of the BCR-ABL Fusion Gene in Chronic Myelogenous Leukemia by Flourescence In Situ Hybridization and Molecular …
S Ozemri Sag, T Yakut, O Gorukmez… - Genetic testing and …, 2015 - liebertpub.com
Aims: Fluorescence in situ hybridization (FISH) and quantitative real-time polymerase chain
reaction (QRT-PCR) were used to diagnose or screen for minimal residual disease (MRD) in …
reaction (QRT-PCR) were used to diagnose or screen for minimal residual disease (MRD) in …
Simple and reliably sensitive diagnosis and monitoring of Philadelphia chromosome-positive cells in chronic myeloid leukemia by interphase fluorescence in situ …
M Yanagi, K Shinjo, A Takeshita, T Tobita, K Yano… - Leukemia, 1999 - nature.com
Philadelphia (Ph) chromosome or the bcr/abl fusion gene is the hallmark of chronic myeloid
leukemia (CML) and serves as a prognostic marker during its treatment. Its detection has …
leukemia (CML) and serves as a prognostic marker during its treatment. Its detection has …
Highly sensitive fluorescence in situ hybridization method to detect double BCR/ABL fusion and monitor response to therapy in chronic myeloid leukemia
GW Dewald, WA Wyatt, AL Juneau… - Blood, The Journal …, 1998 - ashpublications.org
We investigated a new method using fluorescence in situ hybridization and DNA probes that
span the common breakpoints of t (9; 22)(q34; q11. 2) and that detect double BCR/ABL …
span the common breakpoints of t (9; 22)(q34; q11. 2) and that detect double BCR/ABL …
Fluorescence in situ hybridization patterns of BCR/ABL1 fusion in chronic myelogenous leukemia at diagnosis
Background: Chronic myelogenous leukemia (CML) is characterised by the t (9; 22)(q34;
q11. 2) which results in the formation of the BCR/ABL1 fusion gene. Occasionally, the t (9; …
q11. 2) which results in the formation of the BCR/ABL1 fusion gene. Occasionally, the t (9; …
Standardization criteria for the detection of BCR/ABL fusion in interphase nuclei of chronic myelogenous leukemia patients by fluorescence in situ hybridization
N Cohen, I Novikov, I Hardan, A Esa… - Cancer genetics and …, 2000 - Elsevier
Fluorescence in situ hybridization (FISH), as a new clinical test, is not presently
standardized. For practical reasons, each laboratory must build its own criteria. In this work …
standardized. For practical reasons, each laboratory must build its own criteria. In this work …
Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia …
LLP Siu, ESK Ma, WS Wong, MH Chan, KF Wong - BMC Hematology, 2009 - Springer
Background We studied the application of the BCR-ABL1+ 9q34 tri-colour dual fusion
fluorescence in situ hybridization (FISH) system in the characterization of fusion signal …
fluorescence in situ hybridization (FISH) system in the characterization of fusion signal …
Fluorescent in situ hybridization in the diagnosis, prognosis, and treatment monitoring of chronic myeloid leukemia
AP Landstrom, A Tefferi - Leukemia & lymphoma, 2006 - Taylor & Francis
The unique molecular characteristic of chronic myeloid leukemia (CML), the disease-
causing ABL (9q34) to BCR (22q11) translocation, has provided an invaluable tool for …
causing ABL (9q34) to BCR (22q11) translocation, has provided an invaluable tool for …
Conventional cytogenetics and FISH in the detection of BCR/ABL fusion in chronic myeloid leukemia (CML)
HFL Mark, RA Sokolic, Y Mark - Experimental and molecular pathology, 2006 - Elsevier
Chronic myeloid leukemia (CML) is the prototype cytogenetic malignancy. Even before the
development of basic G-banding techniques, CML was found to be associated with a …
development of basic G-banding techniques, CML was found to be associated with a …