Radiochemistry: A Hot Field with Opportunities for Cool Chemistry

GD Bowden, PJH Scott, E Boros - ACS Central Science, 2023 - ACS Publications
Recent Food and Drug Administration (FDA) approval of diagnostic and therapeutic
radiopharmaceuticals and concurrent miniaturization of particle accelerators leading to …

[图书][B] Radiopharmaceutical chemistry

JS Lewis, AD Windhorst, BM Zeglis - 2019 - books.google.com
This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical
successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the …

Pipeline Impact of Radiolabeled Compounds in Drug Discovery and Development

S Vaidyanathan, A Reed - ACS Medicinal Chemistry Letters, 2022 - ACS Publications
The long-lived radionuclides tritium and carbon-14 have been used for many years in
pharmaceutical research and development for making key efficacy and toxicological …

[图书][B] Nuclear Excitation Functions for the Production of Novel Medical Radionuclides

AS Voyles - 2018 - search.proquest.com
The future of nuclear medicine would appear to be the paradigm of personalized medicine—
targeted radionuclide therapy to spare healthy tissue, and theranostic medicine, which pairs …

Unconventional nuclides for radiopharmaceuticals

JP Holland, MJ Williamson, JS Lewis - Molecular imaging, 2010 - journals.sagepub.com
Rapid and widespread growth in the use of nuclear medicine for both diagnosis and therapy
of disease has been the driving force behind burgeoning research interests in the design of …

Total Radiosynthesis: Thinking Outside 'the Box'

SH Liang, N Vasdev - Australian journal of chemistry, 2015 - CSIRO Publishing
The logic of total synthesis transformed a stagnant state of chemistry when there was a
paucity of methods and reagents to synthesize pharmaceuticals. Molecular imaging by …

Re‐thinking the role of radiometal isotopes: Towards a future concept for theranostic radiopharmaceuticals

J Notni, HJ Wester - Journal of Labelled Compounds and …, 2018 - Wiley Online Library
The potential and future role of certain metal radionuclides, for example, 44Sc, 89Zr, 86Y,
64Cu, 68Ga, 177Lu, 225Ac, and 213Bi, and several terbium isotopes has been …

Synthesis of C-11 and F-18 labelled compounds for biomedical applications: Current status and challenges for the future

TJ Ruth, MJ Adam - Journal of radioanalytical and nuclear chemistry, 1996 - Springer
The synthesis of 11 C and 18 F labelled compounds for biomedical applications is a rapidly
growing field with applications in Neurology, Cardiology, Oncology and the study of human …

[PDF][PDF] Therapeutic and diagnostic radiopharmaceuticals

A Keresztes, A Borics, C Tömböly - 2015 - real.mtak.hu
Medical application of ionizing radiation and radioactive isotopes were considered almost
immediately after their discovery. The intense research interest in radioactivity, materials …

A nuclear chocolate box: the periodic table of nuclear medicine

PJ Blower - Dalton Transactions, 2015 - pubs.rsc.org
Radioisotopes of elements from all parts of the periodic table find both clinical and research
applications in radionuclide molecular imaging and therapy (nuclear medicine). This article …