Noncoding RNAs as novel biomarkers in prostate cancer

CGH Rönnau, GW Verhaegh… - BioMed research …, 2014 - Wiley Online Library
Prostate cancer (PCa) is the second most common diagnosed malignant disease in men
worldwide. Although serum PSA test dramatically improved the early diagnosis of PCa, it …

Noncoding RNAs in prostate cancer: the long and the short of it

EM Bolton, AV Tuzova, AL Walsh, T Lynch… - Clinical Cancer Research, 2014 - AACR
As the leading culprit in cancer incidence for American men, prostate cancer continues to
pose significant diagnostic, prognostic, and therapeutic tribulations for clinicians. The vast …

[HTML][HTML] The non-coding transcriptome of prostate cancer: implications for clinical practice

IV Bijnsdorp, ME van Royen, GW Verhaegh… - Molecular diagnosis & …, 2017 - Springer
Prostate cancer (PCa) is the most common type of cancer and the second leading cause of
cancer-related death in men. Despite extensive research, the molecular mechanisms …

[HTML][HTML] Pathological bases and clinical impact of long noncoding RNAs in prostate cancer: a new budding star

T Xu, C Lin, S Cheng, J Min, L Li, X Meng, C Huang… - Molecular cancer, 2018 - Springer
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides. Recent
advances in the non-protein coding part of human genome analysis have discovered …

Clinical prospects of long noncoding RNAs as novel biomarkers and therapeutic targets in prostate cancer

V Mouraviev, B Lee, V Patel, D Albala… - Prostate cancer and …, 2016 - nature.com
Background: The lack of sensitive and specific biomarkers for prostate cancer (PCa) has led
to over-diagnosis and overtreatment with uncertain benefit. Therefore, biomarkers for early …

[HTML][HTML] The use of long non-coding RNAs as prognostic biomarkers and therapeutic targets in prostate cancer

C Arriaga-Canon, IA De La Rosa-Velázquez… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Prostate cancer is the most common cancer in men and the second leading cause of cancer-
related deaths. The most used biomarker to detect prostate cancer is Prostate Specific …

Deciphering the function of non-coding RNAs in prostate cancer

J Ramalho-Carvalho, B Fromm, R Henrique… - Cancer and Metastasis …, 2016 - Springer
The advent of next-generation sequencing methods is fuelling the discovery of multiple non-
coding RNA transcripts with direct implication in cell biology and homeostasis. This new …

[HTML][HTML] Long noncoding RNAs in prostate cancer: overview and clinical implications

B Malik, FY Feng - Asian journal of andrology, 2016 - journals.lww.com
Prostate cancer is the second most common cause of cancer mortality among men in the
United States. While many prostate cancers are indolent, an important subset of patients …

[HTML][HTML] Emerging players in prostate cancer: long non-coding RNAs

T Sun, H Ye, CL Wu, GSM Lee… - American journal of …, 2014 - ncbi.nlm.nih.gov
Recent observations of novel long non-coding RNAs (lncRNAs) have considerably altered
our understanding of cell biology. The role of lncRNAs as tumor suppressors or oncogenes …

[HTML][HTML] RNAs as candidate diagnostic and prognostic markers of prostate cancer—from cell line models to liquid biopsies

MCJ Lim, AM Baird, J Aird, J Greene, D Kapoor… - Diagnostics, 2018 - mdpi.com
The treatment landscape of prostate cancer has evolved rapidly over the past five years. The
explosion in treatment advances has been witnessed in parallel with significant progress in …