Early (< 4 weeks) versus standard (≥ 4 weeks) endoscopically centered step-up interventions for necrotizing pancreatitis

G Trikudanathan, P Tawfik, SK Amateau… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Current guidelines for necrotizing pancreatitis (NP) recommend delay in
drainage±necrosectomy until 4 or more weeks after initial presentation to allow collections to …

Superiority of step-up approach vs open necrosectomy in long-term follow-up of patients with necrotizing pancreatitis

RA Hollemans, OJ Bakker, MA Boermeester, TL Bollen… - Gastroenterology, 2019 - Elsevier
Background & Aims In a 2010 randomized trial (the PANTER trial), a surgical step-up
approach for infected necrotizing pancreatitis was found to reduce the composite endpoint of …

A step-up approach or open necrosectomy for necrotizing pancreatitis

HC Van Santvoort, MG Besselink… - New England journal …, 2010 - Mass Medical Soc
Background Necrotizing pancreatitis with infected necrotic tissue is associated with a high
rate of complications and death. Standard treatment is open necrosectomy. The outcome …

Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial

S van Brunschot, J van Grinsven, HC van Santvoort… - The Lancet, 2018 - thelancet.com
Background Infected necrotising pancreatitis is a potentially lethal disease and an indication
for invasive intervention. The surgical step-up approach is the standard treatment. A …

[HTML][HTML] Immediate versus postponed intervention for infected necrotizing pancreatitis

L Boxhoorn, SM van Dijk, J van Grinsven… - … England Journal of …, 2021 - Mass Medical Soc
Background Infected necrotizing pancreatitis is a potentially lethal disease that is treated
with the use of a step-up approach, with catheter drainage often delayed until the infected …

Interventions for necrotizing pancreatitis: summary of a multidisciplinary consensus conference

ML Freeman, J Werner, HC Van Santvoort, TH Baron… - Pancreas, 2012 - journals.lww.com
Pancreatic and peripancreatic necrosis may result in significant morbidity and mortality in
patients with acute pancreatitis. Many recommendations have been made for management …

A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome

HC Van Santvoort, OJ Bakker, TL Bollen, MG Besselink… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Treatment of patients with necrotizing pancreatitis has become
more conservative and less invasive, but there are few data from prospective studies to …

Timing of catheter drainage in infected necrotizing pancreatitis

J Van Grinsven, HC Van Santvoort… - Nature reviews …, 2016 - nature.com
Acute pancreatitis is the most common gastrointestinal indication for hospital admission, and
infected pancreatic and/or extrapancreatic necrosis is a potentially lethal complication …

Minimally invasive'step-up approach'versus maximal necrosectomy in patients with acute necrotising pancreatitis (PANTER trial): design and rationale of a …

MGH Besselink, HC van Santvoort, VB Nieuwenhuijs… - BMC surgery, 2006 - Springer
Background The initial treatment of acute necrotizing pancreatitis is conservative.
Intervention is indicated in patients with (suspected) infected necrotizing pancreatitis. In the …

Diagnostic strategy and timing of intervention in infected necrotizing pancreatitis: an international expert survey and case vignette study

J van Grinsven, S van Brunschot, OJ Bakker, TL Bollen… - Hpb, 2015 - Wiley Online Library
Background The optimal diagnostic strategy and timing of intervention in infected necrotizing
pancreatitis are subject to debate. A survey was performed on these topics amongst a group …