Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease

R Ramanathan, AH Ali, JA Ibdah - International Journal of Molecular …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …

Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease

I Grattagliano, LP Montezinho, PJ Oliveira… - Biochemical …, 2019 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the excessive
accumulation of triglycerides in hepatocytes. NAFLD is the most frequent chronic liver …

Molecular insights into the role of mitochondria in non-alcoholic fatty liver disease

J Lee, JS Park, YS Roh - Archives of pharmacal research, 2019 - Springer
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most common cause of
fatal liver diseases such as cirrhosis, liver cancer, and indications for orthotopic liver …

Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy

Y Zheng, S Wang, J Wu, Y Wang - Journal of Translational Medicine, 2023 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …

Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?

A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

Mitochondria‐mediated pathogenesis and therapeutics for non‐alcoholic fatty liver disease

Z Li, Y Li, HX Zhang, JR Guo, CWK Lam… - Molecular nutrition & …, 2019 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) has become a worldwide epidemic over the last
decade. Remarkable progress has been made in understanding the pathogenesis of …

[HTML][HTML] Nonalcoholic fatty liver disease and mitochondrial dysfunction

Y Wei, RS Rector, JP Thyfault… - World journal of …, 2008 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) includes hepatic steatosis, nonalcoholic
steatohepatitis (NASH), fibrosis, and cirrhosis. NAFLD is the most common liver disorder in …

Role of mitochondria in nonalcoholic fatty liver disease

F Nassir, JA Ibdah - International journal of molecular sciences, 2014 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) affects about 30% of the general population in the
United States and includes a spectrum of disease that includes simple steatosis, non …

Nonalcoholic fatty liver disease: pathogenesis and therapeutics from a mitochondria‐centric perspective

AM Gusdon, K Song, S Qu - Oxidative medicine and cellular …, 2014 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) describes a spectrum of disorders characterized by
the accumulation of triglycerides within the liver. The global prevalence of NAFLD has been …

[HTML][HTML] Mitochondria in non-alcoholic fatty liver disease

ICM Simões, A Fontes, P Pinton, H Zischka… - The international journal …, 2018 - Elsevier
NAFLD is a common disease in Western society and ranges from steatosis to steatohepatitis
and to end-stage liver disease. The molecular mechanisms that cause the progression of …