Bone marrow mesenchymal stem cell-derived exosomes attenuate LPS-induced ARDS by modulating macrophage polarization through inhibiting glycolysis in …

H Deng, L Wu, M Liu, L Zhu, Y Chen, H Zhou, X Shi… - Shock, 2020 - journals.lww.com
Macrophages play a key role in the development of sepsis-induced acute respiratory
distress syndrome (ARDS). Recent evidence has proved that glycolysis plays an important …

Exosomes derived from pro‐inflammatory bone marrow‐derived mesenchymal stem cells reduce inflammation and myocardial injury via mediating macrophage …

R Xu, F Zhang, R Chai, W Zhou, M Hu… - Journal of cellular …, 2019 - Wiley Online Library
Exosomes are served as substitutes for stem cell therapy, playing important roles in
mediating heart repair during myocardial infarction injury. Evidence have indicated that …

Differential Lung Protective Capacity of Exosomes Derived from Human Adipose Tissue, Bone Marrow, and Umbilical Cord Mesenchymal Stem Cells in Sepsis …

H Deng, L Zhu, Y Zhang, L Zheng, S Hu… - Oxidative medicine …, 2022 - Wiley Online Library
Exosomes derived from human mesenchymal stem cells (hMSCs) have the capacity to
regulate various biological events associated with sepsis‐induced acute respiratory distress …

Exosomes from adipose-derived stem cells alleviate the inflammation and oxidative stress via regulating Nrf2/HO-1 axis in macrophages

K Shen, Y Jia, X Wang, J Zhang, K Liu, J Wang… - Free Radical Biology …, 2021 - Elsevier
ADSCs exosomes, an important means of intercellular communication, can regulate an
array of biological processes, including promoting tissue repairs and regeneration, and …

Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation

F Eshghi, S Tahmasebi, M Alimohammadi, S Soudi… - Life Sciences, 2022 - Elsevier
Background Sepsis is a debilitating systemic inflammation that resulted from infection or
injury. Despite many advances in treatment, the resulting mortality rate has remained high …

BMSC‐derived exosomes ameliorate LPS‐induced acute lung injury by miR‐384‐5p‐controlled alveolar macrophage autophagy

X Liu, C Gao, Y Wang, L Niu, S Jiang… - Oxidative Medicine and …, 2021 - Wiley Online Library
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common critical
diseases. Bone marrow mesenchymal stem cell (BMSC) transplantation is previously shown …

[HTML][HTML] Exosomes from human umbilical cord mesenchymal stem cells attenuate the inflammation of severe steroid-resistant asthma by reshaping macrophage …

B Dong, C Wang, J Zhang, J Zhang, Y Gu… - Stem Cell Research & …, 2021 - Springer
Background Severe, steroid-resistant asthma (SSRA) is a serious clinical problem in asthma
management. Affected patients have severe clinical symptoms, worsened quality of life, and …

[HTML][HTML] Exosomes from mmu_circ_0001359-modified ADSCs attenuate airway remodeling by enhancing FoxO1 signaling-mediated M2-like macrophage activation

Y Shang, Y Sun, J Xu, X Ge, Z Hu, J Xiao, Y Ning… - … Therapy-Nucleic Acids, 2020 - cell.com
Asthma is the most common chronic disease and is characterized by airway remodeling and
chronic inflammation. Increasingly, studies have found that the activation and M1 phenotypic …

[HTML][HTML] Exosomes released by bone marrow mesenchymal stem cells attenuate lung injury induced by intestinal ischemia reperfusion via the TLR4/NF-κB pathway

J Liu, T Chen, P Lei, X Tang… - International journal of …, 2019 - ncbi.nlm.nih.gov
Purpose: Acute lung injury (ALI) is a primary component of multiple organ dysfunction
syndromes triggered by intestinal ischemia-reperfusion (IIR) which results in high mortality …

[HTML][HTML] Exosomes from adipose-derived mesenchymal stem cells alleviate sepsis-induced lung injury in mice by inhibiting the secretion of IL-27 in macrophages

X Wang, D Liu, XH Zhang, LM Yang, Z Xia… - Cell Death …, 2022 - nature.com
Acute lung injury (ALI) represents a frequent sepsis-induced inflammatory disorder.
Mesenchymal stromal cells (MSCs) elicit anti-inflammatory effects in sepsis. This study …