[HTML][HTML] Neuroprotective Effects of β-caryophyllene against dopaminergic neuron injury in a murine model of Parkinson's disease induced by MPTP

JM Viveros-Paredes, RE González-Castañeda… - Pharmaceuticals, 2017 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative disorders and is
characterized by the loss of dopaminergic neurons in the substantia nigra (SN). Although the …

β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson …

S Ojha, H Javed, S Azimullah, ME Haque - Molecular and cellular …, 2016 - Springer
Parkinson disease (PD) is a neurodegenerative disease characterized by progressive
dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The …

β-Caryophyllene exerts protective antioxidant effects through the activation of NQO1 in the MPTP model of Parkinson's disease

ME Flores-Soto, JA Corona-Angeles… - Neuroscience …, 2021 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder, caused by the selective death of
dopaminergic neurons in the substantia nigra pars compacta. β-caryophyllene (BCP) is a …

[HTML][HTML] Benefits of VCE-003.2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: Possible …

C García, M Gómez-Cañas, S Burgaz… - Journal of …, 2018 - Springer
Background Neuroprotection with cannabinoids in Parkinson's disease (PD) has been
afforded predominantly with antioxidant or anti-inflammatory cannabinoids. In the present …

[HTML][HTML] β-Caryophyllene (BCP) ameliorates MPP+ induced cytotoxicity

G Wang, W Ma, J Du - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Parkinson's disease (PD) is one of the most common neurodegenerative diseases resulting
from the continuous death of dopaminergic neurons in substantia nigra. MPP+ (1-methyl-4 …

[HTML][HTML] Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in …

H Javed, S Azimullah, ME Haque… - Frontiers in neuroscience, 2016 - frontiersin.org
The cannabinoid type two receptors (CB2), an important component of the endocannabinoid
system, have recently emerged as neuromodulators and therapeutic targets for …

[HTML][HTML] Proanthocyanidins exert a neuroprotective effect via ROS/JNK signaling in MPTP‑induced Parkinson's disease models in vitro and in vivo

H Chen, J Xu, Y Lv, P He, C Liu… - Molecular …, 2018 - spandidos-publications.com
The pathological alterations of Parkinson's disease (PD) predominantly manifest as a loss of
dopaminergic neurons in the substantia nigra, which may be caused by oxidative stress …

Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile

Y Cheng, G He, X Mu, T Zhang, X Li, J Hu, B Xu… - Neuroscience …, 2008 - Elsevier
1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) causes the damage of dopaminergic
neurons as seen in Parkinson's disease (PD). Oxidative stress has been implicated in the …

Neuroprotective effects of echinacoside in the mouse MPTP model of Parkinson's disease

X Geng, X Tian, P Tu, X Pu - European Journal of Pharmacology, 2007 - Elsevier
In the present study, we investigated the neuroprotective effects of echinacoside, a
phenylethanoid glycoside extracted from the medicinal Chinese herb Cistanches salsa …

β-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2 receptor activation and the PPARγ pathway

Y Cheng, Z Dong, S Liu - Pharmacology, 2014 - karger.com
Background/Aims: The activation of cannabinoid receptor 2 (CB2) has the beneficial effect of
reducing neuroinflammatory response in the treatment of Alzheimer's disease (AD) and is …