From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy

T Efferth - Seminars in cancer biology, 2017 - Elsevier
Artemisia annua L. is used throughout Asia and Africa as tea and press juice to treat malaria
and related symptomes (fever, chills). Its active ingredient, artemisinin (ARS), has been …

Anticancer activity of artemisinin and its derivatives

S Slezáková, J Ruda-Kucerova - Anticancer research, 2017 - ar.iiarjournals.org
Artemisinin is an extract from the plant Artemisia annua. With its semi-synthetic derivatives,
they form a group of well-known and efficacious antimalarial drugs. Recent studies have …

A comprehensive overview of Artemisinin and its derivatives as anticancer agents

Z Zeng, D Chen, L Chen, B He, Y Li - European Journal of Medicinal …, 2023 - Elsevier
Artemisinin is the crucial ingredient of artemisia annua, a traditional Chinese medicine used
for the therapy of malaria in China for hundreds of years. In recent years, the anticancer …

Cytotoxic activity of secondary metabolites derived from Artemisia annua L. towards cancer cells in comparison to its designated active constituent artemisinin

T Efferth, F Herrmann, A Tahrani, M Wink - Phytomedicine, 2011 - Elsevier
Artemisia annua L.(sweet wormwood, qinhao) has traditionally been used in Chinese
medicine. The isolation of artemisinin from Artemisia annua and its worldwide accepted …

[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

AM Posadino, R Giordo, G Pintus… - Biomedicine & …, 2023 - Elsevier
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

Artemisinin and its derivatives: A promising cancer therapy

BH Kiani, WK Kayani, AU Khayam, E Dilshad… - Molecular Biology …, 2020 - Springer
The world is experiencing a cancer epidemic and an increase in the prevalence of the
disease. Cancer remains a major killer, accounting for more than half a million deaths …

[HTML][HTML] Artemisinin and its synthetic derivatives as a possible therapy for cancer

E Konstat-Korzenny, JA Ascencio-Aragón… - Medical …, 2018 - mdpi.com
To assess the possibility of using the antimalarial drug artemisinin and its synthetic
derivatives as antineoplastic drugs. A Pubmed and Google Scholar (1983–2018) search …

[HTML][HTML] Antitumor activity of an Artemisia annua herbal preparation and identification of active ingredients

SJ Lang, M Schmiech, S Hafner, C Paetz, C Steinborn… - Phytomedicine, 2019 - Elsevier
Background Artemisia annua L. has gained increasing attention for its anticancer activity.
However, beside artemisinin, less is known about the possible bioactive ingredients of …

Cancer combination therapies with artemisinin-type drugs

T Efferth - Biochemical pharmacology, 2017 - Elsevier
Artemisia annua L. is a Chinese medicinal plant, which is used throughout Asia and Africa
as tea or press juice to treat malaria. The bioactivity of its chemical constituent, artemisinin is …

Antitumor activity of artemisinin and its derivatives: from a well‐known antimalarial agent to a potential anticancer drug

MP Crespo-Ortiz, MQ Wei - BioMed Research International, 2012 - Wiley Online Library
Improvement of quality of life and survival of cancer patients will be greatly enhanced by the
development of highly effective drugs to selectively kill malignant cells. Artemisinin and its …