Stem cell therapy may replace lost photoreceptors and preserve residual photoreceptors
during retinal degeneration (RD). Unfortunately, the degenerative microenvironment …

Stem cell therapy may be used potentially to treat retinal degeneration and restore vision.
Since embryonic stem cells (ESCs) can differentiate into almost any cell types, including …

Embryonic stem (ES) cells differentiate into all cell types of the body during development,
including those of the central nervous system (CNS). After transplantation, stem cells have …

Loss of photoreceptors due to retinal degeneration is a major cause of untreatable
blindness. Cell replacement therapy, using pluripotent stem cell-derived photoreceptor cells …

Retinal dystrophies often lead to blindness. Developing therapeutic interventions to restore
vision is therefore of paramount importance. Here we demonstrate the ability of pluripotent …

Replacing defective retinal pigment epithelial (RPE) cells with those derived from human
embryonic stem cells (hESCs) or human-induced pluripotent stem cells (hiPSCs) is a …

Retinal degenerations and optic neuropathies often lead to death of photoreceptors or
retinal ganglion cells, respectively. Stem cell therapies are showing promise for these …

Purpose: To investigate whether sheets of retina organoids derived from human embryonic
stem cells (hESCs) can differentiate, integrate, and improve visual function in an …

Irreversible blindness caused by loss of photoreceptors may be amenable to cell therapy.
We previously demonstrated retinal repair and restoration of vision through transplantation …

Cell replacement therapy is a promising treatment for irreversible retinal cell death in diverse
diseases, such as age-related macular degeneration (AMD), Stargardt's disease, retinitis …