Chronic kidney disease (CKD) has become a global public health challenge. While primary
glomerular disease (PGD) is one of the leading causes of CKD, the specific pathogenesis of …

Glomerulonephritis (GN) is one of the most common origins of chronic kidney disease and
its careful evaluation is crucial for prognostic and therapeutic purposes, with the renal biopsy …

Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

The kidney glomerulus is the site of plasma filtration and production of primary urine in the
kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but …

The World Health Organization has estimated mortality and burden of chronic kidney
disease (CKD) in 2002 and predicted it will rank 13th in 2030 instead of 17th in 2002 among …

Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

In this article, the benefits of urinary proteomics in comparison with kidney biopsy are
discussed. The majority of urinary proteins are generated by the kidney, hence the urinary …

Precision medicine is since long an ongoing refinement of classical medicine, integrating
improved and more detailed pathophysiological understanding with rapid technological …

Kidney research is entering an era of 'big data'and molecular omics data can provide
comprehensive insights into the molecular footprints of cells. In contrast to transcriptomics …

There is intense interest in applying proteomics to urine analysis in order to promote a better
understanding of kidney disease processes, develop new biomarkers for diagnosis and …