Anticancer drug resistance almost invariably emerges and poses major obstacles towards
curative therapy of various human malignancies. In the current review we will distinguish …

Intrinsic anticancer drug resistance appearing prior to chemotherapy as well as acquired
resistance due to drug treatment, remain the dominant impediments towards curative cancer …

Advanced cancer is still considered an incurable disease because of its metastatic spread to
distal organs and progressive gain of chemoresistance. Even though considerable treatment …

Introduction: Cancer remains the leading cause of death worldwide. Numerous therapeutic
strategies that include smart biological treatments toward specific cellular pathways are …

Cancer nanomedicines approved so far minimize toxicity, but their efficacy is often limited by
physiological barriers posed by the tumour microenvironment. Here, we discuss how these …

Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

Nanomedicine employs nanotechnologies to develop innovative applications, and more
specifically nano-objects in the field of human health, through exploitation of the physical …

Multidrug resistance (MDR), which significantly decreases the efficacy of anticancer drugs
and causes tumor recurrence, has been a major challenge in clinical cancer treatment with …

Highlights•A systematic review on how new generation molecular nanomedicine allows
chemoresistant cancer management.•Recent developments in molecular targeting …