Circular RNAs in kidney disease and cancer

AJ van Zonneveld, M Kölling, R Bijkerk… - Nature Reviews …, 2021 - nature.com
Circular RNAs (circRNAs) are a class of endogenously expressed regulatory RNAs with a
single-stranded circular structure. They are generated by back splicing and their expression …

Circular RNA in renal diseases

J Jin, H Sun, C Shi, H Yang, Y Wu, W Li… - Journal of cellular …, 2020 - Wiley Online Library
Circular RNA (circRNA) is a newly described type of non‐coding RNA. Active research is
greatly enriching the current understanding of the expression and role of circRNA, and a …

Circular RNAs in renal cell carcinoma: implications for tumorigenesis, diagnosis, and therapy

Y Wang, Y Zhang, P Wang, X Fu, W Lin - Molecular Cancer, 2020 - Springer
Renal cell carcinoma (RCC) is the most common malignant kidney tumor and has a high
incidence rate. Circular RNAs (circRNAs) are noncoding RNAs with widespread distribution …

Circular RNA and its mechanisms in disease: from the bench to the clinic

B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …

Circular RNAs in physiology and non-immunological diseases

L Chen, C Huang, G Shan - Trends in Biochemical Sciences, 2022 - cell.com
Circular RNAs (circRNAs) are covalently closed single-stranded RNAs. Four subclasses of
circRNAs have been identified in animal cells, and they have unique features in their …

Circular RNAs: expression, localization, and therapeutic potentials

Q Yang, F Li, AT He, BB Yang - Molecular therapy, 2021 - cell.com
Circular RNAs (circRNAs) are RNAs with a unique circular structure that is generated from
back-splicing processes. These circular molecules were discovered more than 40 years ago …

[HTML][HTML] Biogenesis and function of circular RNAs in health and in disease

G Haddad, JM Lorenzen - Frontiers in pharmacology, 2019 - frontiersin.org
Circular RNAs (circRNAs) are a class of non-coding RNA that were previously thought to be
insignificant byproducts of splicing errors. However, recent advances in RNA sequencing …

Circular RNA: an important player with multiple facets to regulate its parental gene expression

T Shao, Y Pan, X Xiong - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), a novel type of endogenous RNAs with covalently closed-loop
structures, have become a new research hotspot in the RNA world. Their diversity, stability …

Circular RNAs open a new chapter in cardiovascular biology

S Aufiero, YJ Reckman, YM Pinto… - Nature Reviews …, 2019 - nature.com
Circular RNAs (circRNAs) are emerging as a new class of non-coding RNA molecules. This
unusual class of RNA species is generated by a back-splicing event of one or two exons …

The emerging landscape of circular RNA in cardiovascular diseases

M Zhou, JM Yang, X Xiong - Journal of molecular and cellular cardiology, 2018 - Elsevier
Circular RNAs (circRNAs), a large novel type of endogenous transcripts, have become a
new research hotspot in the field of RNA biology. CircRNAs are mainly generated from …