Associations between birth weight and CVD in adult life are supported by experiments
showing that undernutrition in fetal life programmes blood pressure. In rats, the feeding of a …

Intrauterine growth retardation associated with maternal undernutrition is proposed to play a
significant role in the aetiology of hypertension and CHD. Animal experiments suggest that …

Programming of adult blood pressure by maternal protein restriction: Role of nephrogenesis.
Background Modest maternal protein restriction leads to hypertension and a reduced …

Epidemiological evidence suggests that hypertension and coronary heart disease are
programmed by exposure to a poor diet during intrauterine life. It has been proposed that the …

Epidemiological studies have indicated that susceptibility of human adults to hypertension
and cardiovascular disease may result from intrauterine growth restriction and low birth …

Studies have shown that the risk of hypertension in adulthood can be affected by the in utero
environment. It is established that hypertension is linked to compromised kidney function …

Environmental perturbations during early mammalian development can affect aspects of
offspring growth and cardiovascular health. We have demonstrated previously that maternal …

Exposure to undernutrition during fetal life has been proposed as an underlying cause of
adult hypertension. Epidemiological studies demonstrating relationships between low birth …

Modest maternal dietary protein restriction in the rat leads to hypertension in adult male
offspring. The purpose of this study was to determine whether female rats are resistant to …

Epidemiological data in humans and experiments in laboratory animals have demonstrated
that the developmental programming of hypertension may occur as a consequence of …