Aptamers as modular components of therapeutic nucleic acid nanotechnology
M Panigaj, MB Johnson, W Ke, J McMillan… - Therapeutic RNA …, 2021 - taylorfrancis.com
Nucleic acids play a central role in all domains of life, either as genetic blueprints or as
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …
regulators of various biochemical pathways. The 826chemical makeup of ribonucleic acid …
[图书][B] The aptamer handbook: functional oligonucleotides and their applications
S Klussmann - 2006 - books.google.com
In The Aptamer Handbook, leading scientists from academia as well as biotech and pharma
companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides …
companies introduce the revolutionary concept of designing RNA and DNA oligonucleotides …
Nanotechnology and aptamers: applications in drug delivery
E Levy-Nissenbaum, AF Radovic-Moreno… - Trends in …, 2008 - cell.com
Nucleic acid ligands, also known as aptamers, are a class of macromolecules that are being
used in several novel nanobiomedical applications. Aptamers are characterized by high …
used in several novel nanobiomedical applications. Aptamers are characterized by high …
Aptamer therapeutics advance
JF Lee, GM Stovall, AD Ellington - Current opinion in chemical biology, 2006 - Elsevier
Aptamers are selected nucleic acid binding species with affinities and specificities for protein
targets that rival those of monoclonal antibodies. Furthermore, aptamers have definite …
targets that rival those of monoclonal antibodies. Furthermore, aptamers have definite …
Oligonucleotide aptamers: new tools for targeted cancer therapy
H Sun, X Zhu, PY Lu, RR Rosato, W Tan… - Molecular Therapy-Nucleic …, 2014 - cell.com
Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …
[HTML][HTML] Nucleic acid aptamers: New methods for selection, stabilization, and application in biomedical science
HY Kong, J Byun - Biomolecules & therapeutics, 2013 - ncbi.nlm.nih.gov
The adoption of oligonucleotide aptamer is well on the rise, serving an ever increasing
demand for versatility in biomedical field. Through the SELEX (Systematic Evolution of …
demand for versatility in biomedical field. Through the SELEX (Systematic Evolution of …
Nucleic acid aptamers as tools and drugs: recent developments
M Rimmele - Chembiochem, 2003 - Wiley Online Library
Nucleic acid aptamers are molecules that bind to their ligands with high affinity and
specificity. Unlike other functional nucleic acids such as antisense oligonucleotides …
specificity. Unlike other functional nucleic acids such as antisense oligonucleotides …
Nucleic acid aptamers: an emerging frontier in cancer therapy
The last two decades have witnessed the development and application of nucleic acid
aptamers in a variety of fields, including target analysis, disease therapy, and molecular and …
aptamers in a variety of fields, including target analysis, disease therapy, and molecular and …
Aptamers and SELEX in chemistry & biology
Nucleic acid aptamers, or simply aptamers, are oligonucleotides that bind specific ligands
that vary from small molecules to proteins. An aptamer for a specific ligand is routinely …
that vary from small molecules to proteins. An aptamer for a specific ligand is routinely …
Aptamer chemistry
P Röthlisberger, M Hollenstein - Advanced drug delivery reviews, 2018 - Elsevier
Aptamers are single-stranded DNA or RNA molecules capable of tightly binding to specific
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …
targets. These functional nucleic acids are obtained by an in vitro Darwinian evolution …