Detection of host cell gene/HPV DNA methylation markers: a promising triage approach for cervical cancer
L Zhang, W Tan, H Yang, S Zhang, Y Dai - Frontiers in Oncology, 2022 - frontiersin.org
Cervical cancer is the most prevalent gynecologic malignancy, especially in women of low-
and middle-income countries (LMICs). With a better understanding of the etiology and …
and middle-income countries (LMICs). With a better understanding of the etiology and …
[HTML][HTML] Credentialing of DNA methylation assays for human genes as diagnostic biomarkers of cervical intraepithelial neoplasia in high-risk HPV positive women
N Vasiljević, D Scibior-Bentkowska, AR Brentnall… - Gynecologic …, 2014 - Elsevier
Objective Testing for high risk human papillomavirus (HR-HPV) is increasing; however due
to limitations in specificity there remains a need for better triage tests. Research efforts have …
to limitations in specificity there remains a need for better triage tests. Research efforts have …
DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort
RW van Leeuwen, A Oštrbenk, M Poljak… - … Journal of Cancer, 2019 - Wiley Online Library
Objective triage strategies are required to prevent unnecessary referrals for colposcopy in
population‐based screening programs using primary high‐risk human papillomavirus …
population‐based screening programs using primary high‐risk human papillomavirus …
Combined CADM1/MAL Methylation and Cytology Testing for Colposcopy Triage of High-Risk HPV-Positive Women
LMA De Strooper, AT Hesselink, J Berkhof… - … Biomarkers & Prevention, 2014 - AACR
Primary screening for high-risk human papillomavirus (hrHPV) requires a triage protocol.
Repeat cytology testing at baseline and after 6 to 12 months has emerged as a reasonable …
Repeat cytology testing at baseline and after 6 to 12 months has emerged as a reasonable …
Methylation marker analysis and HPV16/18 genotyping in high-risk HPV positive self-sampled specimens to identify women with high grade CIN or cervical cancer
VMJ Verhoef, DAM Heideman, FJ van Kemenade… - Gynecologic …, 2014 - Elsevier
Objectives Methylation marker analysis using bi-marker panel MAL/miR-124-2 is a
promising triage test for identifying cervical (pre) cancer in high-risk human papillomavirus …
promising triage test for identifying cervical (pre) cancer in high-risk human papillomavirus …
A four‐gene methylation marker panel as triage test in high‐risk human papillomavirus positive patients
JJH Eijsink, A Lendvai, V Deregowski… - … journal of cancer, 2012 - Wiley Online Library
Cervical neoplasia‐specific biomarkers, eg DNA methylation markers, with high sensitivity
and specificity are urgently needed to improve current population‐based screening on (pre) …
and specificity are urgently needed to improve current population‐based screening on (pre) …
Evaluation of six methylation markers derived from genome-wide screens for detection of cervical precancer and cancer
S Dick, L Verhoef, LMA De Strooper… - …, 2020 - Taylor & Francis
Aim: To evaluate the triage performance of six host-cell DNA methylation markers derived
from two genome-wide discovery screens for detection of cervical precancer (cervical …
from two genome-wide discovery screens for detection of cervical precancer (cervical …
Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis
H Kelly, Y Benavente, MA Pavon, S De Sanjose… - British journal of …, 2019 - nature.com
Background To conduct a meta-analysis of performance of DNA methylation in women with
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …
high-grade cervical intraepithelial neoplasia (CIN2+). Methods Medline and Embase …
Performance of DNA methylation‐based biomarkers in the cervical cancer screening program of northern Portugal: A feasibility study
S Salta, L Maia‐Moço… - … Journal of Cancer, 2021 - Wiley Online Library
Cervical cancer remains a health concern. Effective screening programs are critical to
reduce the incidence and mortality. High‐risk HPV (hr‐HPV) testing as primary screening …
reduce the incidence and mortality. High‐risk HPV (hr‐HPV) testing as primary screening …
A systematic review and meta-analysis of the diagnostic effectiveness of human papillomavirus methylation biomarkers for detection of cervical cancer
CRT Hillyar, SS Kanabar, KR Pufal, AW Lawson… - …, 2022 - Taylor & Francis
Background: The aim of this systematic review and meta-analysis was to assess the
evidence for the diagnostic effectiveness of human papillomavirus (HPV) methylation …
evidence for the diagnostic effectiveness of human papillomavirus (HPV) methylation …
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