The pros and cons of preimplantation genetic testing for aneuploidy: clinical and laboratory perspectives

Z Rosenwaks, AH Handyside, F Fiorentino… - Fertility and …, 2018 - fertstert.org
Aneuploidy is a major source of adverse outcomes in human reproduction. The impact is so
severe, that the American College of Obstetricians and Gynecologists and the Society for …

[HTML][HTML] The use of preimplantation genetic testing for aneuploidy (PGT-A): a committee opinion

A Penzias, K Bendikson, S Butts, C Coutifaris… - Fertility and sterility, 2018 - Elsevier
The value of preimplantation genetic testing for aneuploidy (PGT-A) as a screening test for in
vitro fertilization (IVF) patients has yet to be determined. Several studies demonstrate higher …

[HTML][HTML] Preimplantation genetic testing for aneuploidy: challenges in clinical practice

H Yang, AT DeWan, MM Desai, SH Vermund - Human Genomics, 2022 - Springer
Preimplantation genetic testing for aneuploidy (PGT-A) has been used widely during in vitro
fertilization procedures in assisted reproductive centers throughout the world. Despite its …

Preimplantation genetic testing for aneuploidy: It's déjà vu all over again!

GL Schattman - Fertility and Sterility, 2019 - fertstert.org
In this issue of the journal, we finally get the results of the long-awaited STAR, or Single-
Embryo Transfer of Euploid Embryo, trial (1). I applaud the authors for publishing this …

Preimplantation genetic testing for aneuploidy: a review

JM Kemper, BJ Vollenhoven… - … & Gynecological Survey, 2019 - journals.lww.com
Objective This review seeks to describe the historical development of PGT-A and to analyze
and summarize the current published literature. Conclusions At times during its infancy, PGT …

We have reached a dead end for preimplantation genetic testing for aneuploidy

N Gleicher, DH Barad, P Patrizio… - Human …, 2022 - academic.oup.com
The hypothesis of preimplantation genetic testing for aneuploidy (PGT-A) was first proposed
20 years ago, suggesting that during IVF elimination of aneuploid embryos prior to transfer …

Preimplantation genetic testing for aneuploidy (PGT‐A): the biology, the technology and the clinical outcomes

HA Homer - Australian and New Zealand Journal of Obstetrics …, 2019 - Wiley Online Library
Preimplantation genetic testing for aneuploidy (PGT‐A) seeks to identify preimplantation
embryos with a normal chromosome complement (euploid) during in vitro fertilisation (IVF) …

Non-invasive prenatal testing in the context of IVF and PGT-A

D Kimelman, ME Pavone - Best Practice & Research Clinical Obstetrics & …, 2021 - Elsevier
The high incidence of chromosome aneuploidy in human gametes and embryos is a major
cause of in vitro fertilization (IVF) failure and miscarriage. In order to improve live birth rates …

Preimplantation genetic testing for aneuploidy (PGT-A)—a single-center experience

J Nair, S Shetty, CI Kasi, N Thondehalmath… - Journal of Assisted …, 2022 - Springer
Purpose The aim of this study was to determine the prevalence and nature of human
embryonic aneuploidy based on the preimplantation genetic testing for aneuploidy (PGT-A) …

Preimplantation genetic testing for aneuploidy: a canadian fertility and andrology society guideline

C Chan, M Ryu, R Zwingerman - Reproductive BioMedicine Online, 2021 - Elsevier
The objective of this guideline from the Canadian Fertility and Andrology Society is to
synthesize the evidence on preimplantation genetic testing for aneuploidies (PGT-A) using …