Mammalian Krüppel-like factors in health and diseases

BB McConnell, VW Yang - Physiological reviews, 2010 - journals.physiology.org
The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …

A Network of Krüppel-like Factors (Klfs): Klf8 is repressed by Klf3 and activated by Klf1 in vivo

SA Eaton, APW Funnell, N Sue, H Nicholas… - Journal of Biological …, 2008 - ASBMB
Transcription factors of the Sp/Klf (Krüppel-like factor) family regulate biological processes
such as hematopoiesis, adipogenesis, and stem cell maintenance. Here we show that Bklf …

Krüppel-like factors in mammalian stem cells and development

AB Bialkowska, VW Yang, SK Mallipattu - Development, 2017 - journals.biologists.com
Krüppel-like factors (KLFs) are a family of zinc-finger transcription factors that are found in
many species. Recent studies have shown that KLFs play a fundamental role in regulating …

Krüppel-like factors: crippling and uncrippling metabolic pathways

NM Pollak, M Hoffman, IJ Goldberg… - JACC: Basic to …, 2018 - jacc.org
Krüppel-like factors (KLFs) are deoxyribonucleic acid–binding transcriptional factors that
regulate various pathways that control metabolism and other cellular mechanisms. Various …

Krüppel-like factors: three fingers in control

SK Swamynathan - Human genomics, 2010 - Springer
Krüppel-like factors (KLFs), members of the zinc-finger family of transcription factors capable
of binding GC-rich sequences, have emerged as critical regulators of important functions all …

Role of Krüppel-like factors in leukocyte development, function, and disease

Z Cao, X Sun, B Icli, AK Wara… - Blood, The Journal of …, 2010 - ashpublications.org
The Krüppel-like transcription factor (KLF) family participates in diverse aspects of cellular
growth, development, differentiation, and activation. Recently, several groups have identified …

Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation

AM Ghaleb, MO Nandan, S Chanchevalap, WB Dalton… - Cell research, 2005 - nature.com
Krüppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription
factors with diverse regulatory functions in cell growth, proliferation, differentiation, and …

Krüppel-like factor 4 (KLF4): What we currently know

AM Ghaleb, VW Yang - Gene, 2017 - Elsevier
Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

Roles of Krüppel‐like factor 4 in normal homeostasis, cancer and stem cells

PM Evans, C Liu - Acta biochimica et biophysica Sinica, 2008 - Wiley Online Library
Krüppel‐like factor 4 (KLF4) is a zinc finger‐type transcription factor expressed in a variety of
tissues, including the epithelium of the intestine and the skin, and it plays an important role …

The diverse functions of Krüppel‐like factors 4 and 5 in epithelial biology and pathobiology

BB McConnell, AM Ghaleb, MO Nandan, VW Yang - Bioessays, 2007 - Wiley Online Library
The Krüppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger
transcription factors that regulate numerous biological processes including proliferation …