Design and characterization of Lactotransferrin peptide-loaded dextran-docosahexaenoic acid nanoparticles: an immune modulator for hepatic damage

OA Madkhali, SS Moni, MH Sultan, MA Bakkari… - Scientific Reports, 2023 - nature.com
The primary objective of this research was to create injectable delivery formulations using
Lactotransferrin (LTF) peptide-loaded dextran nanoparticles coated with docosahexaenoic …

Tannic acid and vitamin E loaded PLGA nanoparticles ameliorate hepatic injury in a chronic alcoholic liver damage model via EGFR-AKT-STAT3 pathway

S Nag, K Manna, M Saha, K Das Saha - Nanomedicine, 2020 - Taylor & Francis
Aim: Tannic acid and vitamin E loaded-poly D, L-lactide-co-glycolic acid (PLGA)
nanoparticles (NP) were developed to achieve hepatoprotection in alcoholic liver disease …

Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses

F Wu, SA Wuensch, M Azadniv… - Molecular …, 2009 - ACS Publications
We aim to define the role of Kupffer cells in intrahepatic antigen presentation, using the
selective delivery of antigen to Kupffer cells rather than other populations of liver antigen …

Preparation, characterization, and in vitro/vivo studies of oleanolic acid-loaded lactoferrin nanoparticles

X Xia, H Liu, H Lv, J Zhang, J Zhou… - … design, development and …, 2017 - Taylor & Francis
Oleanolic acid (OA), a pentacyclic triterpene, is used to safely and economically treat
hepatopathy. However, OA, a Biopharmaceutics Classification System IV category drug, has …

In-vitro evaluation of solid lipid nanoparticles: Ability to encapsulate, release and ensure effective protection of peptides in the gastrointestinal tract

C Dumont, S Bourgeois, H Fessi, PY Dugas… - International Journal of …, 2019 - Elsevier
Peptides are rarely orally administrated due to rapid degradation in the gastrointestinal tract
and low absorption at the epithelial border. The objective of this study was to encapsulate a …

Lactoferrin: the conductor of the immunological system?

S Farnaud, RW Evans - 2005 - westminsterresearch.westminster.ac …
Zariwala, M., Bendre, H., Markiv, A., Farnaud, S., Renshaw, D., Taylor, KMG and
Somavarapu, S. 2018. Hydrophobically modified chitosan nanoliposomes for intestinal drug …

Enhanced Cellular Uptake and Transport of Bovine lactoferrin using pectin-and Chitosan-modified solid lipid nanoparticles

X Yao, C Bunt, M Liu, SY Quek, J Shaw, J Cornish… - Pharmaceutics, 2023 - mdpi.com
Aim: The aim of this project is to use pectin-and chitosan-modified solid lipid nanoparticles
for bovine lactoferrin to enhance its cellular uptake and transport. Methods: Solid lipid …

[HTML][HTML] Solid lipid nanoparticles enhance the resistance of oat-derived peptides that inhibit dipeptidyl peptidase IV in simulated gastrointestinal fluids

L Su, F Zhou, M Yu, R Ge, J He, B Zhang… - Journal of Functional …, 2020 - Elsevier
In this study, we investigated the effects of solid lipid nanoparticle (SLN) nanocrystallization
on the stability of two fractions of oat globulin-derived peptides. ie, OGL, with molecular …

Decorin-loaded poly lactic-co-glycolic acid nanoparticles modified by anti-alpha fetoprotein antibody: Preparation, proliferation inhibition and induced apoptosis …

Q Yang, S Wang, Y Wang, Y Qu, J Xue… - Journal of Pharmacy …, 2017 - academic.oup.com
Objectives Decorin (DCN) is a negative regulatory factor for the growth of cancer cells and
can inhibit the proliferation, metastasis of cancer cells and angiogenesis in cancer tissues …

In vivo biodistribution, anti-inflammatory, and hepatoprotective effects of liver targeting dexamethasone acetate loaded nanostructured lipid carrier system

M Wang, Y Jin, Y Yang, C Zhao, H Yang… - International journal …, 2010 - Taylor & Francis
We aimed to evaluate whether the enhancement of the liver accumulation and anti-
inflammatory activity of dexamethasone acetate (DXMA) could be achieved by incorporating …