Topical tretinoin is the most commonly used retinoid for acne. However, its irritative potential
on the applied area and the barrier properties of the stratum corneum limit its use. The …

An attempt was made to pharmaceutically develop a topical liposomal tretinoin (TRE) gel
and clinically evaluate the developed formulation for the treatment of acne in patients …

Purpose: The aims of this experimental work were the incorporation and full characterization
of the system Tretinoin-in-dimethyl-beta-cyclodextrin-in-ultradeformable vesicles (Tretinoin …

Background The aim of this study was to develop and optimize deformable liposome for
topical delivery of tretinoin. Methods Liposomal formulations were designed based on the …

Here, we assessed the efficacy and safety of Nano lipid carrier (NLC) drug delivery system
containing tretinoin (NLC-TRE) in comparison with the conventional 0.05% tretinoin cream …

Tretinoin (TRT) is a widely used retinoid for the topical treatment of acne, photo-aged skin,
psoriasis and skin cancer which makes it a good candidate for topical formulation. Yet side …

Frequently occurring skin irritancy and flare-up reactions impede the use of topical tretinoin
for acne vulgaris due to poor patient compliance. Liposome encapsulation improves …

The influence of liposome composition, size, lamellarity and charge on the (trans) dermal
delivery of tretinoin (TRA) was studied. For this purpose we studied both multilamellar (MLV) …

Cosmetic skin care products currently in the market demonstrate an increasing trend toward
antiaging products. Selection of the right formulation approach is the key to successful …

Background: The clinical efficacy of the topical tretinoin is widely studied and has been well
established for many therapeutic interventions, among some, photoaging, acne, and …