The past 5 years has witnessed an advance in our understanding of alpha1G (Ca v 3.1),
alpha1H (Ca v 3.2), and alpha1l (Ca v 3.3), the pore-forming subunits of T-type or low …

Although T-type calcium channel currents were observed almost 30 years ago, the genes
that encode the pore-forming subunits have only been recently reported. When expressed in …

Within the family of voltage-gated calcium channels (VGCCs), L-type channels (L-VGCCs)
represent a well-established therapeutic target for calcium channel blockers, which are …

T-type, or low-voltage-activated (LVA), tiny and transient Ca2+ currents pare more and more
recognised as universal players in a plethora of cell functions and are also more and more …

Voltage-gated calcium channels are found in the plasma membrane of many excitable and
non-excitable cells. When open, they permit influx of calcium, which acts as a second …

Voltage-gated calcium channels are essential for cou-pling membrane depolarization to the
influx of calcium in all excitable cells. The calcium that flows into excitable cells through …

T-type channels are distinguished among voltage-gated Ca2+ channels by their low voltage
thresholds for activation and inactivation, fast inactivation and small single channel …

This review will first describe the importance of Ca2+ entry for function of excitable cells, and
the subsequent discovery of voltage-activated calcium conductances in these cells. This …

Low voltage-activated, T-type, calcium channels are thought to be involved in pacemaker
activity, low threshold Ca 2+ spikes, neuronal oscillations and resonance, and rebound burst …

It has been suggested that the auxiliary subunits of high voltage-activated (HVA) calcium
channels modulate T-type, low voltage-activated (LVA) calcium channels. Such a regulation …