Abstract Human factor Xa (FXa) is a serine protease of the common coagulation pathway.
FXa is known to activate prothrombin to thrombin, which eventually leads to the formation of …

SARS-CoV-2 infection (COVID-19) results in local and systemic activation of inflammation
and coagulation. In this review article, we will discuss the potential role of coagulation factor …

Serine proteases (SP), including furin, trypsin, and TMPRSS2 cleave the SARS-CoV-2 spike
(S) protein, enabling the virus to enter cells. Here, we show that factor (F) Xa, an SP involved …

Introduction: Thrombosis is a common causal pathology for stroke, acute coronary syndrome
and venous thromboembolism disorders, which are the leading cause of death worldwide …

Thromboembolic diseases are the leading causes of morbidity and mortality in the
developed world. Anticoagulants provide effective treatment for venous or arterial …

As a pathological coagulation process, thrombus can lead to many serious diseases,
including ischemic stroke, acute myocardial infarction (AMI), acute coronary syndrome …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) commonly complicates
with coagulopathy. A syndrome called Long-COVID-19 is emerging recently in COVID-19 …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a novel envelope virus
that causes coronavirus disease 2019 (COVID‐19). Hallmarks of COVID‐19 are a puzzling …

Over the last decade, significant advances have been made in the pharmacotherapy of
acute coronary syndromes (ACS). Although aspirin and unfractionated heparin have been …

Coagulation factor Xa (fXa) and thrombin (thr) are widely expressed in pulmonary tissues,
where they may catalyze, together with the transmembrane serine protease 2 (TMPRSS2) …