Phototheranostics: active targeting of orthotopic glioma using biomimetic proteolipid nanoparticles

Y Jia, X Wang, D Hu, P Wang, Q Liu, X Zhang, J Jiang… - ACS …, 2018 - ACS Publications
Advances in phototheranostics revolutionized glioma intraoperative fluorescence imaging
and phototherapy. However, the lack of desired active targeting agents for crossing the …

Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier

J Lai, G Deng, Z Sun, X Peng, J Li, P Gong, P Zhang… - Biomaterials, 2019 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers, and Blood-Brain Barrier (BBB) is
the main obstacle to diagnose and treat GBM, hence scientists are making great efforts to …

[HTML][HTML] Nanoliposomes co-encapsulating CT imaging contrast agent and photosensitizer for enhanced, imaging guided photodynamic therapy of cancer

H Xu, TY Ohulchanskyy, A Yakovliev, R Zinyuk… - Theranostics, 2019 - ncbi.nlm.nih.gov
Fluorescence (FL) and X-ray computed tomography (CT) imaging-guided photodynamic
therapy (PDT) can provide a powerful theranostic tool to visualize, monitor, and treat cancer …

Rapamycin/DiR loaded lipid-polyaniline nanoparticles for dual-modal imaging guided enhanced photothermal and antiangiogenic combination therapy

J Wang, F Guo, M Yu, L Liu, F Tan, R Yan… - Journal of Controlled …, 2016 - Elsevier
Imaging-guided photothermal therapy (PTT) has promising application for treating tumors.
Nevertheless, so far imaging-guided photothermal drug-delivery systems have been …

NIR‐II Perylene Monoimide‐Based Photothermal Agent with Strengthened Donor–Acceptor Conjugation for Deep Orthotopic Glioblastoma Phototheranostics

J Guan, C Liu, C Ji, W Zhang, Z Fan, P He, Q Ouyang… - Small, 2023 - Wiley Online Library
Extensive efforts have been devoted to the design of organic photothermal agents (PTAs)
that absorb in the second near‐infrared (NIR‐II) bio‐window, which can provide deeper …

[HTML][HTML] Targeted delivery of functionalized upconversion nanoparticles for externally triggered photothermal/photodynamic therapies of brain glioblastoma

YC Tsai, P Vijayaraghavan, WH Chiang, HH Chen… - Theranostics, 2018 - ncbi.nlm.nih.gov
Therapeutic efficacy of glioblastoma multiforme (GBM) is often severely limited by poor
penetration of therapeutics through blood-brain barrier (BBB) into brain tissues and lack of …

Allomelanin-based biomimetic nanotherapeutics for orthotopic glioblastoma targeted photothermal immunotherapy

M Sun, Y Li, W Zhang, X Gu, R Wen, K Zhang, J Mao… - Acta Biomaterialia, 2023 - Elsevier
Immune checkpoint blockade (ICB) therapy has shown great potential in the treatment of
malignant tumors, but its therapeutic effect on glioblastoma (GBM) is unsatisfactory because …

Indocyanine green loaded SPIO nanoparticles with phospholipid-PEG coating for dual-modal imaging and photothermal therapy

Y Ma, S Tong, G Bao, C Gao, Z Dai - Biomaterials, 2013 - Elsevier
A biodegradable nanotheranostic agent has been successfully constructed for
fluorescence/magnetic resonance dual-modal imaging guided photothermal therapy by …

Brain‐targeted aggregation‐induced‐emission nanoparticles with near‐infrared imaging at 1550 nm boosts orthotopic glioblastoma theranostics

J Wang, Y Liu, M Morsch, Y Lu… - Advanced …, 2022 - Wiley Online Library
A remaining challenge in the treatment of glioblastoma multiforme (GBM) is surmounting the
blood–brain barrier (BBB). Such a challenge prevents the development of efficient …

[HTML][HTML] Liposomal IR-780 as a highly stable nanotheranostic agent for improved photothermal/photodynamic therapy of brain tumors by convection-enhanced …

YJ Lu, CC Chuang, JP Chen - Cancers, 2021 - mdpi.com
Simple Summary To improve the use of hydrophobic photosensitizer IR-780 in
photothermal/photodynamic therapy (PTT/PDT), we entrap IR-780 within the lipid bilayer of …