Pigment epithelium-derived factor (PEDF) is an extracellular multifunctional protein
belonging to the serpin superfamily with demonstrable neurotrophic, gliastatic …

Pigment epithelium‐derived factor (PEDF) is a 50 kDa secreted glycoprotein that belongs to
the non‐inhibitory serpin family group. PEDF has been described as a natural angiogenesis …

The extracellular pigment epithelium-derived factor (PEDF) displays retina survival activity
by interacting with receptor proteins on cell surfaces. We have previously reported that …

Pigment epithelium-derived factor (PEDF), a noninhibitory member of the serpin superfamily,
is the most potent inhibitor of angiogenesis in the mammalian ocular compartment. It also …

Pigment epithelium-derived factor (PEDF) is a 50-kDa protein encoded by a single gene that
shows strong conservation across phyla from fish to mammals. It is secreted by the retinal …

purpose. The neurotrophic activity of pigment epithelium–derived factor (PEDF), an
extracellular factor present in the retina, is mediated by binding to cell-surface receptors in …

The pigment epithelium–derived factor (PEDF) belongs to the superfamily of serine protease
inhibitors (serpin). There have been 2 distinct functions attributed to this factor, which can act …

Pigment epithelial-derived factor (PEDF) is a 50-kDa secreted glycoprotein that belongs to
the non-inhibitory serpin. It has an α/β core serine-protease inhibitor domain, 3 major β …

Retinal pigment epithelial (RPE) cells form a functional complex with photoreceptor neurons
of the retina, interacting through the interphotoreceptor matrix (IPM). We now provide …

Pigment epithelium-derived factor (PEDF), a neurite-promoting factor, has an amino acid
primary structure that is related to members of the serine protease inhibitor (serpin) family …