Gap‐junction disassembly and connexin 43 dephosphorylation induced by 18β‐glycyrrhetinic acid

X Guan, S Wilson, KK Schlender… - … in cooperation with the …, 1996 - Wiley Online Library
Gap‐junction channels connect the interiors of adjacent cells and can be arranged into
aggregates or plaques consisting of hundreds to thousands of channel particles. The …

Gap junction turnover, intracellular trafficking, and phosphorylation of connexin43 in brefeldin A-treated rat mammary tumor cells.

DW Laird, M Castillo, L Kasprzak - The Journal of cell biology, 1995 - rupress.org
Intercellular gap junction channels are thought to form when oligomers of connexins from
one cell (connexons) register and pair with connexons from a neighboring cell en route to …

Gap junction endocytosis and lysosomal degradation of connexin43-P2 in WB-F344 rat liver epithelial cells treated with DDT and lindane

X Guan, RJ Ruch - Carcinogenesis, 1996 - academic.oup.com
Abstract Treatment of WB-F344 rat liver epithelial cells with DDT (1, l-bis (p-chlorophenyl)-2,
2, 2-trichloroethane) or lindane induces a loss of gap junction plaques and a decrease in the …

Localization and function of the connexin 43 gap‐junction protein in normal and various oncogene‐expressing rat liver epithelial cells

AW de Feijter, DF Matesic, RJ Ruch… - … in cooperation with …, 1996 - Wiley Online Library
Clones of rat liver epithelial cells genotypically altered by mutation or by a variety of
oncogenes were analyzed by microinjection‐dye transfer, immunofluorescence confocal …

[HTML][HTML] The gap junction-independent tumor-suppressing effect of connexin 43

YW Zhang, M Kaneda, I Morita - Journal of Biological Chemistry, 2003 - ASBMB
The gap junction gene connexin 43 (Cx43) showed tumor-suppressing effects on various
tumor cell lines. We have previously demonstrated that Cx43 inhibited expression of S …

Connexin43 in MDCK cells: regulation by a tumor-promoting phorbol ester and Ca2+.

VM Berthoud, ML Ledbetter, EL Hertzberg… - European journal of …, 1992 - europepmc.org
Prior to confluence, cultures of Madin Darby canine kidney (MDCK) cells expressed gap
junctional communication, as assessed by fluorescent dye transfer, as well as relatively high …

Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43)

RP Huang, Y Fan, MZ Hossain, A Peng, ZL Zeng… - Cancer research, 1998 - AACR
Connexins (cx), structural components of gap junction, are believed to play a role in the
regulation of cell proliferation and suppression of the neoplastic phenotype. We used human …

Interplay between PKC and the MAP kinase pathway in Connexin43 phosphorylation and inhibition of gap junction intercellular communication

S Sirnes, A Kjenseth, E Leithe, E Rivedal - Biochemical and biophysical …, 2009 - Elsevier
Gap junction channels are made of a family proteins called connexins. The best-studied type
of connexin, Connexin43 (Cx43), is phosphorylated at several sites in its C-terminus. The …

Aberrant expression and localization of connexin43 and connexin30 in a rat glioma cell line

G Mennecier, M Derangeon, V Coronas… - … in cooperation with …, 2008 - Wiley Online Library
Gap junctions are cellular structures which permit direct exchanges of small molecules from
cytoplasm to cytoplasm in most of the cells of metazoan organisms. For four decades, it has …

Two inhibitors of gap junctional intercellular communication, TPA and endosulfan: different effects on phosphorylation of connexin 43 in the rat liver epithelial cell line …

K Kenne, R Fransson-Steen, S Honkasalo… - …, 1994 - academic.oup.com
The skin tumour promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) and the chlorinated
insecticide, endosulfan, are two potent Inhibitors of gap junctional intercellular …