[HTML][HTML] Rationally Designed Novel Antimicrobial Peptides Targeting Chitin Synthase for Combating Soybean Phytophthora Blight

Y Ran, K Shehzadi, JH Liang, MJ Yu - International Journal of Molecular …, 2024 - mdpi.com
Soybean phytophthora blight is a severe menace to global agriculture, causing annual
losses surpassing USD 1 billion. Present crop loss mitigation strategies primarily rely on …

[HTML][HTML] In vitro and in silico investigation of effects of antimicrobial peptides from Solanaceae plants against rice sheath blight pathogen Rhizoctinia solani

T Mustapha, T Zubair, RB Patil, BA Bhongade… - Plos one, 2024 - journals.plos.org
Rhizoctonia solani, the causative agent of sheath blight disease in rice, poses a significant
threat to agricultural productivity. Traditional management approaches involving chemical …

[HTML][HTML] In-Silico Validation of Prosopis ciniraria Therapeutic Peptides Against Fungal Cell Wall: Better Treatment Strategy for Fungal Diseases

A Joshi, DS Solanki, P Gehlot, J Singh… - International Journal of …, 2022 - Springer
Prosopis cineraria commonly known as Druce are valuable herb that holds antibacterial
role, antifungal properties. We identified different peptides from this plant by deploying …

Mechanism Analysis of Antimicrobial Peptide NoPv1 Related to Potato Late Blight through a Computer-Aided Study

JS Zhou, HL Wen, MJ Yu - International Journal of Molecular Sciences, 2024 - mdpi.com
Phytophthora infestans (Mont.) de Bary, the oomycotic pathogen responsible for potato late
blight, is the most devastating disease of potato production. The primary pesticides used to …

Engineering Phenothiazine-Based Functional Mimics of Host Defense Peptides as New Agrochemical Candidates: Design, Synthesis, and Antibacterial Evaluation

WB Shao, RS Luo, J Meng, XK Lv… - Journal of Agricultural …, 2023 - ACS Publications
In the protracted “arms race” between host and plant pathogenic bacteria, host organisms
have evolved powerful weapons known as host defense peptides (HDPs). However, natural …

Cloning, functional characterization and screening of potential inhibitors for Chilo partellus chitin synthase A using in silico, in vitro and in vivo approaches

S Ranganathan, AV Ilavarasi, BK Palaka… - Journal of …, 2022 - Taylor & Francis
Chitin synthase (CHS) is one of the crucial enzymes that play an essential role in chitin
synthesis during the molting process, and it is considered to be the specific target to control …

Combating fungal phytopathogens with human salivary antimicrobial peptide histatin 5 through a multi-target mechanism

S Chadha - World Journal of Microbiology and Biotechnology, 2023 - Springer
Blast disease caused by Magnaporthe oryzae is a major contributor to decreased crop yield
and rice production globally. The use of chemical fungicides to combat crop pathogens is …

In SilicoDesign and Synthesis of Antifungal Peptides Guided by Quantitative Antifungal Activity

J Zhang, X Sun, H Zhao, X Zhou, Y Zhang… - Journal of Chemical …, 2024 - ACS Publications
Antifungal peptides (AFPs) are emerging as promising candidates for advanced antifungal
therapies because of their broad-spectrum efficacy and reduced resistance development. In …

[HTML][HTML] Carboxypeptidase inhibitors from Solanaceae as a new subclass of pathogenesis related peptide aiming biotechnological targets for plant defense

GS Gomes, PC Espósito… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Plant protease inhibitors play a crucial role in inhibiting proteases produced by
phytopathogens and exhibiting inhibitory effects on nematodes, fungi, and insects, making …

[HTML][HTML] Targeted Amino Acid Substitutions in a Trichoderma Peptaibol Confer Activity against Fungal Plant Pathogens and Protect Host Tissues from Botrytis cinerea …

M De Zotti, L Sella, A Bolzonello, L Gabbatore… - International journal of …, 2020 - mdpi.com
Fungal species belonging to the Trichoderma genus are commonly used as biocontrol
agents against several crop pathogens. Among their secondary metabolites, peptaibols are …